| Type | Description |
|---|---|
| Definition | myosin phosphatase Rho interacting protein |
| Date | Results | Publications |
|---|---|---|
| 2015-02-14 12:36:00 | The B-Raf(V600E) inhibitor dabrafenib selectively inhibits RIP3 and alleviates acetaminophen-induced liver injury. | 24901049 |
| 2012-09-29 10:41:00 | Our data identify M-RIP as a crucial local regulator of the Rho-Rac balance during chemotaxis and antigen recognition. | 22349701 |
| 2011-08-06 11:13:00 | MLCP (myosin light chain phosphatase) activation is counteracted by a previously unrecognized association between MRIP and the inducible kinase NUAK2 | 21242312 |
| 2010-01-21 00:00:00 | p116Rip is an important regulatory component that controls the RhoA signaling pathway, thus regulating MLCP activity and myosin phosphorylation in cells | 15545284 |
| 2010-01-21 00:00:00 | A functional analysis of JNK1 and M-RIP with RNA interference reveals a critical role for this cascade in the invasive behavior of cancer cells. | 18636174 |
| Type | IDs |
|---|---|
| Synonymous | M-RIP, MRIP, RHOIP3, RIP3, p116Rip |
| Gene |
UniProtKB-ID:
MPRIP_HUMAN,
Q8N236_HUMAN
UniprotKB:
Q6WCQ1,
Q8N236
UniParc:
UPI00000722BA,
UPI0000200A77,
UPI0000EE7D8D,
UPI0000366BAD
EMBL:
AC079111,
AB189741,
AY296247,
AK092287,
AB098507,
BC009982,
AC055811,
BC105987,
AL834513,
BC075847
Ensembl:
ENSG00000133030
KO:
hsa:23164
|
| Nucleutide sequences |
EMBL-CDS:
CAD39169.1,
AAH09982.2,
BAD89507.1,
BAC78198.1,
AAQ63176.1,
AAI05988.1,
AAH75847.1,
BAC03851.1
Ensembl_TRS:
ENST00000341712,
ENST00000395811
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000342379,
ENSP00000379156
RefSeq:
XP_011522069.2,
XP_011522068.2,
XP_005256621.3,
NP_001351645.2,
XP_011522064.1,
XP_011522067.1,
XP_011522066.1,
XP_016879882.1,
XP_011522065.1,
NP_055949.2,
NP_958431.2,
XP_005256620.1
|
| Others |
UniRef100:
UniRef100_U6FSN9,
UniRef100_Q6WCQ1
UniRef90:
UniRef90_Q6WCQ1,
UniRef90_U6FSN9
UniRef50:
UniRef50_Q6WCQ1,
UniRef50_U6FSN9
UniGene:
Hs.462341
CCDS:
CCDS32578.1,
CCDS42268.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员