| Type | Description |
|---|---|
| Definition | transmembrane protein 119 |
| Date | Results | Publications |
|---|---|---|
| 2016-08-27 12:33:00 | The first highly pure RNAseq profiles of microglia during development and after immune challenge show Tmem119 gene expression increases during development until P14 and then stabilizes. | 26884166 |
| 2016-05-21 10:31:00 | Obif plays essential roles in the development of multiple tissues, is required for bone mineralization and spermatogenesis. | 26207632 |
| 2015-01-17 10:50:00 | BMP-2 stimulates differentiation of myoblasts into osteoblasts via the PERK-eIF2alpha-ATF4 pathway but in addition stimulates Tmem119, which itself increases ATF4 | 24362451 |
| 2012-10-06 10:22:00 | Data show that Tmem119 promotes the differentiation of myoblasts into osteoblasts and the interaction with the BMP signaling pathway likely occurs downstream of Runx2 and Osterix in myoblasts. | 22579779 |
| 2012-09-15 10:23:00 | Obif plays an essential role in bone formation through regulating osteoblastogenesis. | 22416756 |
| Type | IDs |
|---|---|
| Synonymous | AW208946, BC025600, obif |
| Gene |
UniProtKB-ID:
TM119_MOUSE
UniprotKB:
Q8R138
UniParc:
UPI0000027CD7
EMBL:
AK170712,
AK078473,
BC025600
Ensembl:
ENSMUSG00000054675
KO:
mmu:231633
|
| Nucleutide sequences |
EMBL-CDS:
BAC37292.1,
AAH25600.1,
BAE41970.1
Ensembl_TRS:
ENSMUST00000067853
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000070551
RefSeq:
NP_666274.1,
XP_036020982.1
|
| Others |
UniRef100:
UniRef100_Q8R138
UniRef90:
UniRef90_Q8R138
UniRef50:
UniRef50_Q8R138
UniGene:
Mm.41681
CCDS:
CCDS19554.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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