| Type | Description |
|---|---|
| Definition | golgi associated, gamma adaptin ear containing, ARF binding protein 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-04-20 11:11:00 | SNPs: rs6414624 in EVC and rs78338345 in GGA3 are novel susceptibility loci for type 2 diabetes mellitus in Japanese individuals. | 29273463 |
| 2017-09-02 12:42:00 | In the absence of GGA3, integrins are increasingly retained inside the cell, traffic toward the perinuclear lysosomal compartment and their degradation is enhanced. | 26935970 |
| 2016-10-22 11:17:00 | This work identifies GGA3 as a key player in a novel DXXLL-mediated endosomal sorting machinery that targets TrkA to the plasma membrane, where it prolongs the activation of Akt signaling and survival responses. | 26446845 |
| 2016-08-13 10:55:00 | role of GGA3 in the cell surface export of alpha2B-adrenergic receptor | 26811329 |
| 2014-04-26 11:37:00 | These data indicate that clathrin is required for the function of AP-1- and GGA-coated carriers at the trans-Golgi network but may be dispensable for outward traffic en route to the plasma membrane. | 24407285 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
GGA3_HUMAN,
B7Z456_HUMAN,
A8K6M0_HUMAN
UniprotKB:
Q9NZ52,
B7Z456,
A8K6M0
UniParc:
UPI0001914F8A,
UPI000012B3DF,
UPI0000EE5C3C,
UPI000002AA69,
UPI00019152EA,
UPI00015DA872
EMBL:
AF190864,
AC022211,
AK291685,
AF219139,
CH471099,
AK302278,
AK301895,
BC070044,
D63876,
AF219138,
AK296843
Ensembl:
ENSG00000125447
KO:
hsa:23163
|
| Nucleutide sequences |
EMBL-CDS:
AAH70044.1,
EAW89258.1,
AAF42848.1,
BAH13665.1,
AAF05709.1,
AAF42849.1,
BAA09926.1,
BAH13578.1,
BAH12442.1,
BAF84374.1
Ensembl_TRS:
ENST00000649398,
ENST00000578348,
ENST00000537686,
ENST00000582717,
ENST00000538886
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000438085,
ENSP00000496890,
ENSP00000463288,
ENSP00000446421,
ENSP00000462081
RefSeq:
XP_024306433.1,
XP_016879881.1,
NP_001166174.1,
NP_001278570.1,
XP_016879878.1,
XP_016879879.1,
XP_016879874.1,
NP_001166175.1,
NP_001278571.1,
NP_054720.1,
XP_016879876.1,
XP_016879877.1,
XP_011522865.1,
XP_016879875.1,
NP_619525.1
|
| Others |
UniRef100:
UniRef100_Q9NZ52,
UniRef100_A8K6M0
UniRef90:
UniRef90_Q9NZ52
UniRef50:
UniRef50_Q9NZ52
UniGene:
Hs.87726
CCDS:
CCDS58597.1,
CCDS54164.1,
CCDS11717.1,
CCDS11716.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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