RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination.

BMC Biol     Nila Roy Choudhury , Gregory Heikel , Maryia Trubitsyna , Peter Kubik , Jakub Stanislaw Nowak , Shaun Webb , Sander Granneman , Christos Spanos , Juri Rappsilber , Alfredo Castello , Gracjan Michlewski

Architecture of the human interactome defines protein communities and disease networks.

Nature     Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper

Structural basis for different phosphoinositide specificities of the PX domains of sorting nexins regulating G-protein signaling.

J Biol Chem     Caroline Mas , Suzanne J Norwood , Andrea Bugarcic , Genevieve Kinna , Natalya Leneva , Oleksiy Kovtun , Rajesh Ghai , Lorena E Ona Yanez , Jasmine L Davis , Rohan D Teasdale , Brett M Collins

Discovery and refinement of loci associated with lipid levels.

Nat. Genet.     Cristen J Willer , Ellen M Schmidt , Sebanti Sengupta , Gina M Peloso , Stefan Gustafsson , Stavroula Kanoni , Andrea Ganna , Jin Chen , Martin L Buchkovich , Samia Mora , Jacques S Beckmann , Jennifer L Bragg-Gresham , Hsing-Yi Chang , Ayşe Demirkan , Heleen M Den Hertog , Ron Do , Louise A Donnelly , Georg B Ehret , Tõnu Esko , Mary F Feitosa , Teresa Ferreira , Krista Fischer , Pierre Fontanillas , Ross M Fraser , Daniel F Freitag , Deepti Gurdasani , Kauko Heikkilä , Elina Hyppönen , Aaron Isaacs , Anne U Jackson , Åsa Johansson , Toby Johnson , Marika Kaakinen , Johannes Kettunen , Marcus E Kleber , Xiaohui Li , Jian'an Luan , Leo-Pekka Lyytikäinen , Patrik K E Magnusson , Massimo Mangino , Evelin Mihailov , May E Montasser , Martina Müller-Nurasyid , Ilja M Nolte , Jeffrey R O'Connell , Cameron D Palmer , Markus Perola , Ann-Kristin Petersen , Serena Sanna , Richa Saxena , Susan K Service , Sonia Shah , Dmitry Shungin , Carlo Sidore , Ci Song , Rona J Strawbridge , Ida Surakka , Toshiko Tanaka , Tanya M Teslovich , Gudmar Thorleifsson , Evita G Van den Herik , Benjamin F Voight , Kelly A Volcik , Lindsay L Waite , Andrew Wong , Ying Wu , Weihua Zhang , Devin Absher , Gershim Asiki , Inês Barroso , Latonya F Been , Jennifer L Bolton , Lori L Bonnycastle , Paolo Brambilla , Mary S Burnett , Giancarlo Cesana , Maria Dimitriou , Alex S F Doney , Angela Döring , Paul Elliott , Stephen E Epstein , Gudmundur Ingi Eyjolfsson , Bruna Gigante , Mark O Goodarzi , Harald Grallert , Martha L Gravito , Christopher J Groves , Göran Hallmans , Anna-Liisa Hartikainen , Caroline Hayward , Dena Hernandez , Andrew A Hicks , Hilma Holm , Yi-Jen Hung , Thomas Illig , Michelle R Jones , Pontiano Kaleebu , John J P Kastelein , Kay-Tee Khaw , Eric Kim , Norman Klopp , Pirjo Komulainen , Meena Kumari , Claudia Langenberg , Terho Lehtimäki , Shih-Yi Lin , Jaana Lindström , Ruth J F Loos , François Mach , Wendy L McArdle , Christa Meisinger , Braxton D Mitchell , Gabrielle Müller , Ramaiah Nagaraja , Narisu Narisu , Tuomo V M Nieminen , Rebecca N Nsubuga , Isleifur Olafsson , Ken K Ong , Aarno Palotie , Theodore Papamarkou , Cristina Pomilla , Anneli Pouta , Daniel J Rader , Muredach P Reilly , Paul M Ridker , Fernando Rivadeneira , Igor Rudan , Aimo Ruokonen , Nilesh Samani , Hubert Scharnagl , Janet Seeley , Kaisa Silander , Alena Stančáková , Kathleen Stirrups , Amy J Swift , Laurence Tiret , Andre G Uitterlinden , L Joost van Pelt , Sailaja Vedantam , Nicholas Wainwright , Cisca Wijmenga , Sarah H Wild , Gonneke Willemsen , Tom Wilsgaard , James F Wilson , Elizabeth H Young , Jing Hua Zhao , Linda S Adair , Dominique Arveiler , Themistocles L Assimes , Stefania Bandinelli , Franklyn Bennett , Murielle Bochud , Bernhard O Boehm , Dorret I Boomsma , Ingrid B Borecki , Stefan R Bornstein , Pascal Bovet , Michel Burnier , Harry Campbell , Aravinda Chakravarti , John C Chambers , Yii-Der Ida Chen , Francis S Collins , Richard S Cooper , John Danesh , George Dedoussis , Ulf de Faire , Alan B Feranil , Jean Ferrières , Luigi Ferrucci , Nelson B Freimer , Christian Gieger , Leif C Groop , Vilmundur Gudnason , Ulf Gyllensten , Anders Hamsten , Tamara B Harris , Aroon Hingorani , Joel N Hirschhorn , Albert Hofman , G Kees Hovingh , Chao Agnes Hsiung , Steve E Humphries , Steven C Hunt , Kristian Hveem , Carlos Iribarren , Marjo-Riitta Järvelin , Antti Jula , Mika Kähönen , Jaakko Kaprio , Antero Kesäniemi , Mika Kivimaki , Jaspal S Kooner , Peter J Koudstaal , Ronald M Krauss , Diana Kuh , Johanna Kuusisto , Kirsten O Kyvik , Markku Laakso , Timo A Lakka , Lars Lind , Cecilia M Lindgren , Nicholas G Martin , Winfried März , Mark I McCarthy , Colin A McKenzie , Pierre Meneton , Andres Metspalu , Leena Moilanen , Andrew D Morris , Patricia B Munroe , Inger Njølstad , Nancy L Pedersen , Chris Power , Peter P Pramstaller , Jackie F Price , Bruce M Psaty , Thomas Quertermous , Rainer Rauramaa , Danish Saleheen , Veikko Salomaa , Dharambir K Sanghera , Jouko Saramies , Peter E H Schwarz , Wayne H-H Sheu , Alan R Shuldiner , Agneta Siegbahn , Tim D Spector , Kari Stefansson , David P Strachan , Bamidele O Tayo , Elena Tremoli , Jaakko Tuomilehto , Matti Uusitupa , Cornelia M van Duijn , Peter Vollenweider , Lars Wallentin , Nicholas J Wareham , John B Whitfield , Bruce H R Wolffenbuttel , Jose M Ordovas , Eric Boerwinkle , Colin N A Palmer , Unnur Thorsteinsdottir , Daniel I Chasman , Jerome I Rotter , Paul W Franks , Samuli Ripatti , L Adrienne Cupples , Manjinder S Sandhu , Stephen S Rich , Michael Boehnke , Panos Deloukas , Sekar Kathiresan , Karen L Mohlke , Erik Ingelsson , Gonçalo R Abecasis , Global Lipids Genetics Consortium

Toward an understanding of the protein interaction network of the human liver.

Mol. Syst. Biol.     Jian Wang , Keke Huo , Lixin Ma , Liujun Tang , Dong Li , Xiaobi Huang , Yanzhi Yuan , Chunhua Li , Wei Wang , Wei Guan , Hui Chen , Chaozhi Jin , Juncheng Wei , Wanqiao Zhang , Yongsheng Yang , Qiongming Liu , Ying Zhou , Cuili Zhang , Zhihao Wu , Wangxiang Xu , Ying Zhang , Tao Liu , Donghui Yu , Yaping Zhang , Liang Chen , Dewu Zhu , Xing Zhong , Lixin Kang , Xiang Gan , Xiaolan Yu , Qi Ma , Jing Yan , Li Zhou , Zhongyang Liu , Yunping Zhu , Tao Zhou , Fuchu He , Xiaoming Yang

Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

Mol. Med.     Jed E Rose , Frédérique M Behm , Tomas Drgon , Catherine Johnson , George R Uhl

Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.

Genome Res.     Kouichi Kimura , Ai Wakamatsu , Yutaka Suzuki , Toshio Ota , Tetsuo Nishikawa , Riu Yamashita , Jun-ichi Yamamoto , Mitsuo Sekine , Katsuki Tsuritani , Hiroyuki Wakaguri , Shizuko Ishii , Tomoyasu Sugiyama , Kaoru Saito , Yuko Isono , Ryotaro Irie , Norihiro Kushida , Takahiro Yoneyama , Rie Otsuka , Katsuhiro Kanda , Takahide Yokoi , Hiroshi Kondo , Masako Wagatsuma , Katsuji Murakawa , Shinichi Ishida , Tadashi Ishibashi , Asako Takahashi-Fujii , Tomoo Tanase , Keiichi Nagai , Hisashi Kikuchi , Kenta Nakai , Takao Isogai , Sumio Sugano

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

Genome Res.     Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team

Complete sequencing and characterization of 21,243 full-length human cDNAs.

Nat. Genet.     Toshio Ota , Yutaka Suzuki , Tetsuo Nishikawa , Tetsuji Otsuki , Tomoyasu Sugiyama , Ryotaro Irie , Ai Wakamatsu , Koji Hayashi , Hiroyuki Sato , Keiichi Nagai , Kouichi Kimura , Hiroshi Makita , Mitsuo Sekine , Masaya Obayashi , Tatsunari Nishi , Toshikazu Shibahara , Toshihiro Tanaka , Shizuko Ishii , Jun-ichi Yamamoto , Kaoru Saito , Yuri Kawai , Yuko Isono , Yoshitaka Nakamura , Kenji Nagahari , Katsuhiko Murakami , Tomohiro Yasuda , Takao Iwayanagi , Masako Wagatsuma , Akiko Shiratori , Hiroaki Sudo , Takehiko Hosoiri , Yoshiko Kaku , Hiroyo Kodaira , Hiroshi Kondo , Masanori Sugawara , Makiko Takahashi , Katsuhiro Kanda , Takahide Yokoi , Takako Furuya , Emiko Kikkawa , Yuhi Omura , Kumi Abe , Kumiko Kamihara , Naoko Katsuta , Kazuomi Sato , Machiko Tanikawa , Makoto Yamazaki , Ken Ninomiya , Tadashi Ishibashi , Hiromichi Yamashita , Katsuji Murakawa , Kiyoshi Fujimori , Hiroyuki Tanai , Manabu Kimata , Motoji Watanabe , Susumu Hiraoka , Yoshiyuki Chiba , Shinichi Ishida , Yukio Ono , Sumiyo Takiguchi , Susumu Watanabe , Makoto Yosida , Tomoko Hotuta , Junko Kusano , Keiichi Kanehori , Asako Takahashi-Fujii , Hiroto Hara , Tomo-o Tanase , Yoshiko Nomura , Sakae Togiya , Fukuyo Komai , Reiko Hara , Kazuha Takeuchi , Miho Arita , Nobuyuki Imose , Kaoru Musashino , Hisatsugu Yuuki , Atsushi Oshima , Naokazu Sasaki , Satoshi Aotsuka , Yoko Yoshikawa , Hiroshi Matsunawa , Tatsuo Ichihara , Namiko Shiohata , Sanae Sano , Shogo Moriya , Hiroko Momiyama , Noriko Satoh , Sachiko Takami , Yuko Terashima , Osamu Suzuki , Satoshi Nakagawa , Akihiro Senoh , Hiroshi Mizoguchi , Yoshihiro Goto , Fumio Shimizu , Hirokazu Wakebe , Haretsugu Hishigaki , Takeshi Watanabe , Akio Sugiyama , Makoto Takemoto , Bunsei Kawakami , Masaaki Yamazaki , Koji Watanabe , Ayako Kumagai , Shoko Itakura , Yasuhito Fukuzumi , Yoshifumi Fujimori , Megumi Komiyama , Hiroyuki Tashiro , Akira Tanigami , Tsutomu Fujiwara , Toshihide Ono , Katsue Yamada , Yuka Fujii , Kouichi Ozaki , Maasa Hirao , Yoshihiro Ohmori , Ayako Kawabata , Takeshi Hikiji , Naoko Kobatake , Hiromi Inagaki , Yasuko Ikema , Sachiko Okamoto , Rie Okitani , Takuma Kawakami , Saori Noguchi , Tomoko Itoh , Keiko Shigeta , Tadashi Senba , Kyoka Matsumura , Yoshie Nakajima , Takae Mizuno , Misato Morinaga , Masahide Sasaki , Takushi Togashi , Masaaki Oyama , Hiroko Hata , Manabu Watanabe , Takami Komatsu , Junko Mizushima-Sugano , Tadashi Satoh , Yuko Shirai , Yukiko Takahashi , Kiyomi Nakagawa , Koji Okumura , Takahiro Nagase , Nobuo Nomura , Hisashi Kikuchi , Yasuhiko Masuho , Riu Yamashita , Kenta Nakai , Tetsushi Yada , Yusuke Nakamura , Osamu Ohara , Takao Isogai , Sumio Sugano

An unappreciated role for RNA surveillance.

Genome Biol.     R Tyler Hillman , Richard E Green , Steven E Brenner