| Type | Description |
|---|---|
| Definition | Fraser extracellular matrix complex subunit 1 |
| Date | Results | Publications |
|---|---|---|
| 2016-12-17 11:54:00 | The close correlation between limb bud epidermal blistering, decreased Msx2 expression, and reduced ICD in the Fras1(rdf) hindlimb buds suggests that epithelium detachment from the mesenchyme may create a physical gap that interrupts the transmission of BMP, among other signals, resulting in soft tissue syndactyly. | 26813283 |
| 2014-06-21 11:56:00 | the role of Fras1 in development | 24143185 |
| 2013-06-22 10:48:00 | Targeted deletion of Fras1 in kidney podocytes circumvented skin blistering, renal agenesis, and early death. | 22730198 |
| 2012-08-25 11:28:00 | Report Fras1 up-regulation/Frem down-regulation in nephrons from mice with polycystic kidney disease and Frem2 mutations. | 21993971 |
| 2012-08-25 10:45:00 | The QBRICK, together with Fras1, defines the ability of BMs to bind integrin 81 through modulating the BM assembly of nephronectin, thereby regulating the integrin 81-mediated signals transmitted from the ureteric buds to the metanephric mesenchyme. | 22613833 |
| Type | IDs |
|---|---|
| Synonymous | E130113P14Rik, bl, mKIAA1500 |
| Gene |
UniProtKB-ID:
FRAS1_MOUSE
UniprotKB:
Q80T14
UniParc:
UPI000024FDF2
EMBL:
AC121829,
BC044881,
AC151985,
AK122518,
AC122007,
AC101391,
AJ489280,
AK051850
Ensembl:
ENSMUSG00000034687
KO:
mmu:231470
|
| Nucleutide sequences |
EMBL-CDS:
BAC34788.1,
AAH44881.1,
BAC65800.1,
CAD33519.1
Ensembl_TRS:
ENSMUST00000036019
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000043250
RefSeq:
XP_006534936.1,
XP_017176335.1,
NP_780682.3,
XP_017176336.1
|
| Others |
UniRef100:
UniRef100_Q80T14
UniRef90:
UniRef90_Q80T14
UniRef50:
UniRef50_Q80T14
UniGene:
Mm.291120
CCDS:
CCDS19450.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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