| Type | Description |
|---|---|
| Definition | autophagy related 2A |
| Date | Results | Publications |
|---|---|---|
| 2020-04-11 12:29:00 | N-terminal fragment of ATG2A that supports lipid transfer in vitro is both necessary and fully sufficient to rescue blocked autophagosome biogenesis in ATG2A/ATG2B KO cells | 30952800 |
| 2020-02-29 10:17:00 | Here, the authors demonstrate that human ATG2A is a lipid transfer protein. ATG2A can extract lipids from membrane vesicles and unload them to other vesicles. Lipid transfer by ATG2A is more efficient between tethered vesicles than between untethered vesicles. | 31271352 |
| 2018-07-28 10:12:00 | Authors demonstrate that inhibition of autophagosome completion by Atg2A/B deletion accumulates immature autophagosomal membranes that promote non-canonical caspase-8 activation in response to nutrient starvation via an intracellular death-inducing signaling complex (iDISC). | 28800131 |
| 2018-05-19 11:48:00 | Among polymorphisms identified in the present study, rs76974938 [C/T (D67N)] of C21orf59 and rs188780113 [G/A (R478C)] of ATG2A may be novel determinants of estimated glomerular filtration rate and chronic kidney disease or of the serum concentration of uric acid, respectively. | 28410202 |
| 2018-01-13 11:25:00 | These data provide evidence for additional roles of Atg2A and Atg14L in the formation of early autophagosomal membranes and also in lipid metabolism. | 24776541 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
ATG2A_HUMAN
UniprotKB:
Q2TAZ0
UniParc:
UPI00001D77C0,
UPI00001C0C3B,
UPI0000DA6BA1,
UPI00001C1F21
EMBL:
BC110650,
AB007864,
AK126181,
BC053596,
BC113091,
AP001187,
BC008593,
BC027481
Ensembl:
ENSG00000110046
KO:
hsa:23130
|
| Nucleutide sequences |
EMBL-CDS:
AAH53596.1,
AAI10651.1,
BAC86477.1,
AAH27481.1,
BAA23700.1,
AAH08593.1,
AAI13092.1
Ensembl_TRS:
ENST00000421419,
ENST00000377264
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000366475,
ENSP00000410522
RefSeq:
NP_055919.2,
XP_011543165.1,
NP_001354901.1,
XP_011543168.1,
XP_011543169.1,
NP_001354900.1,
XP_011543167.1,
XP_011543166.1
|
| Others |
UniRef100:
UniRef100_Q2TAZ0
UniRef90:
UniRef90_Q2TAZ0
UniRef50:
UniRef50_Q2TAZ0
UniGene:
Hs.370671
CCDS:
CCDS31602.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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