Type | Description |
---|---|
Definition | TGF-beta activated kinase 1 (MAP3K7) binding protein 2 |
Date | Results | Publications |
---|---|---|
2021-01-02 12:49:00 | A single nucleotide deletion resulting in a frameshift in exon 4 of TAB2 is associated with a polyvalular syndrome. | 31981616 |
2020-03-14 10:45:00 | we deeply dissect the molecular pathogenesis of the TAB2 c.1398dup variant and show that the resulting phenotype is well explained by TAB2 loss-of-function. Our data also offer initial insights on the ECM homeostasis impairment as a molecular mechanism probably underlying a multisystem disorder linked to TAB2. | 31250519 |
2020-02-15 13:19:00 | rs237028 polymorphism in the TAB2 gene was associated with epithelial ovarian cancer susceptibility in Chinese population. | 31485280 |
2019-10-19 11:23:00 | multiple GPCR agonists utilize non-canonical TAB1-TAB2 and TAB1-TAB3-dependent p38 activation to promote endothelial inflammatory responses. | 30760523 |
2018-08-11 10:10:00 | Data indicate an association between TAK1-binding protein 2 (TAB2) mutations and a connective tissue disorder with severe polyvalvular heart disease and subtle facial dysmorphism. | 28386937 |
Type | IDs |
---|---|
Synonymous | CHTD2, MAP3K7IP2, TAB-2 |
Gene |
UniProtKB-ID:
TAB2_HUMAN,
B4DIR9_HUMAN
UniprotKB:
Q9NYJ8,
B4DIR9
UniParc:
UPI0000072F70,
UPI00017A71F8,
UPI0000073C75
EMBL:
DQ314877,
BC035910,
AL031133,
CR457387,
AL117407,
AF241230,
AK315038,
CH471051,
AL138727,
AK295750,
AB018276,
AL139103
Ensembl:
ENSG00000055208
KO:
hsa:23118
|
Nucleutide sequences |
EMBL-CDS:
AAF67176.1,
CAB55907.1,
EAW47805.1,
CAG33668.1,
EAW47806.1,
AAH35910.1,
EAW47807.1,
BAA34453.2,
ABC40736.1,
BAG37521.1,
BAG58581.1
Ensembl_TRS:
ENST00000367456,
ENST00000538427,
ENST00000637181,
ENST00000470466
|
Protein sequencees |
Ensembl_PRO:
ENSP00000445752,
ENSP00000432709,
ENSP00000490618,
ENSP00000356426
RefSeq:
NP_055908.1,
NP_001278963.1,
XP_011533935.1,
NP_001356435.1,
XP_016866081.1,
NP_001278964.1
|
Others |
UniRef100:
UniRef100_Q9NYJ8,
UniRef100_B4DIR9
UniRef90:
UniRef90_F6VE69,
UniRef90_Q9NYJ8
UniRef50:
UniRef50_Q9NYJ8
UniGene:
Hs.269775
CCDS:
CCDS5214.1
|
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