| Type | Description |
|---|---|
| Definition | insulin induced gene 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-08-04 10:08:00 | Intracellular biosynthesis of lipids and cholesterol by Scap and Insig in mesenchymal cells regulates long bone growth and chondrocyte homeostasis. | 29899135 |
| 2015-04-18 11:23:00 | myeloid-cell-specific Insig1-/- mice are more susceptible to HSV-1 infection | 25526307 |
| 2014-03-29 11:46:00 | the essential role of Insig1,2 proteins in the sterol homeostasis of enterocytes. | 24337570 |
| 2013-12-28 10:29:00 | reducing Insig1 mRNA to a similar degree observed in morbidly obese human WAT accelerates adipocyte differentiation and enhances lipogenesis, and consequently, lipid accumulation | 23919961 |
| 2013-05-25 10:32:00 | we consistently observe involvement of gp78 in Insig-1 degradation, we find no substantive evidence to support roles for either gp78 or TRC8 in the robust sterol-accelerated degradation of HMG-CoA reductase. | 23087214 |
| Type | IDs |
|---|---|
| Synonymous | 1810013C12Rik, Insig-1 |
| Gene |
UniProtKB-ID:
INSI1_MOUSE
UniprotKB:
Q8BGI3
UniParc:
UPI000002775F
EMBL:
AF527630,
AK151186,
AK135941,
BC132167,
BC132499,
AK088380,
AK139913
Ensembl:
ENSMUSG00000045294
KO:
mmu:231070
|
| Nucleutide sequences |
EMBL-CDS:
AAN28331.1,
BAE22733.1,
BAE24179.1,
AAI32168.1,
AAI32500.1,
BAC40316.1,
BAE30185.1
Ensembl_TRS:
ENSMUST00000059155
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000061877
RefSeq:
NP_705746.1
|
| Others |
UniRef100:
UniRef100_Q8BGI3
UniRef90:
UniRef90_Q8BGI3
UniRef50:
UniRef50_Q8BGI3
UniGene:
Mm.30221
CCDS:
CCDS19142.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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