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23095 KIF1B

23095

KIF1B

kinesin family member 1B

protein-coding

Homo sapiens

基因描述

Type Description
Definition kinesin family member 1B

研究结论

Date Results Publications
2020-05-16 12:58:00 The Kif1bbeta and Fignl1 loss of function similarly altered zebrafish motor axon pathfinding and increased dynein-based transport velocity of Rab3 vesicles in these navigating axons, pinpointing Fignl1/Kif1bbeta as a dynein speed limiter complex. 31541015
2020-02-22 10:38:00 associations of single nucleotide polymorphisms of KIF1B gene with the severity of clinical manifestations of multiple sclerosis 31934989
2019-11-09 10:13:00 The authors' findings indicate that tumor suppressor KIF1Bbeta plays an important role in intrinsic mitochondria-mediated apoptosis through the regulation of structural and functional dynamics of mitochondria in collaboration with YME1L1. 30859632
2019-10-05 10:59:00 results revealed a significant association between KIF1B rs17401966 polymorphism and susceptibility to HCC under a random-effect allelic model 30947687
2018-10-20 11:59:00 In conclusion, using a panel including 17 susceptibility genes, we documented the presence of somatic mutations in over 50% of pheochromocytomas and paragangliomas (PPGL). We confirmed the high frequency of NF1 somatic mutations and identified KIF1B as the second most frequently mutated gene in PPGL tissues. 28515046

名称对应

Type IDs
Synonymous CMT2, CMT2A, CMT2A1, HMSNII, KLP, NBLST1
Gene
UniProtKB-ID: KIF1B_HUMAN
UniprotKB: O60333
UniParc: UPI000051912B, UPI000013EE7E, UPI000003424C, UPI0000140CB8
EMBL: AB017133, BC001415, BT007174, AK022977, AL358013, AL139424, AF257176, AB040881, AX039604, AB088210, BC115395, AY043362, AY139835, AB011163
Ensembl: ENSG00000054523
KO: hsa:23095
Nucleutide sequences
EMBL-CDS: BAB69038.1, CAC16629.1, AAP35838.1, AAK49332.1, AAK85155.1, BAA25517.2, BAE02543.1, AAI15396.1, AAN17742.1, BAA95972.2, AAH01415.1, BAB14341.1
Ensembl_TRS: ENST00000377093, ENST00000377086, ENST00000263934, ENST00000377081, ENST00000377083
Protein sequencees
Ensembl_PRO: ENSP00000263934, ENSP00000366297, ENSP00000366290, ENSP00000366284, ENSP00000366287
RefSeq: NP_001352881.1, NP_904325.2, NP_001352880.1, NP_055889.2, NP_001352882.1
Others
UniRef100: UniRef100_O60333
UniRef90: UniRef90_O60333
UniRef50: UniRef50_O60333
UniGene: Hs.97858
CCDS: CCDS112.1, CCDS111.1

全选

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研究热度

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