| Type | Description |
|---|---|
| Definition | F-box protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2017-06-10 10:59:00 | F-box only protein 2 (FBXO2), a substrate recognition component of the Skp1-Cul1-F-box protein (SCF) E3 ubiquitin ligase complex, was upregulated in livers of obese mice. Furthermore, using a protein purification approach combined with high-performance liquid chromatography/tandem mass spectrometry, we carried out a system-wide screening of FBXO2 substrates, in which the insulin receptor (IR) was identified as a substrate | 27932386 |
| 2016-05-14 10:11:00 | FBG1 degrades A1AT-Z through a Beclin1-dependent arm of autophagy. | 26295339 |
| 2015-06-20 10:38:00 | The results of this study suggested that Fbxo2 controls the abundance and localization of specific NMDAR subunits in the brain and may influence synapse formation and maintenance. | 25878288 |
| 2014-06-28 10:21:00 | these results suggest that Fbxo2 regulates APP levels and processing in the brain and may play a role in modulating Alzheimer disease pathogenesis. | 24469452 |
| 2013-06-22 12:10:00 | our studies support a non-essential role for FBG1 on the degradation of torsinA and uncover a novel link of FBG1 to the autophagy pathway. | 22917612 |
| Type | IDs |
|---|---|
| Synonymous | FBG1, FBX2, Fbs1, Fbs2, NFB42, Prpl4 |
| Gene |
UniProtKB-ID:
FBX2_MOUSE,
Q3USR5_MOUSE
UniprotKB:
Q80UW2,
Q3USR5
UniParc:
UPI000000BA36
EMBL:
BC046586,
AK140175,
BC027053
Ensembl:
ENSMUSG00000041556
KO:
mmu:230904
|
| Nucleutide sequences |
EMBL-CDS:
AAH46586.1,
AAH27053.1,
BAE24266.1
Ensembl_TRS:
ENSMUST00000047951
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000037377
RefSeq:
XP_006538877.1,
NP_789818.1
|
| Others |
UniRef100:
UniRef100_Q80UW2
UniRef90:
UniRef90_Q80UW2
UniRef50:
UniRef50_Q80UW2
UniGene:
Mm.262287
CCDS:
CCDS18935.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员