| Type | Description |
|---|---|
| Definition | solute carrier family 30 (zinc transporter), member 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-09-14 10:20:00 | This study confirms that ZnT2 is important for normal breast function in women during lactation, and suggests that women who harbor defective variants in ZnT2 may be at-risk for poor lactation performance. | 29476070 |
| 2019-07-20 11:19:00 | ZnT2 is a novel regulator of vacuolar ATPase assembly, driving lysosome biogenesis, acidification, and tissue remodeling during the initiation of mammary gland involution. | 29718697 |
| 2016-02-20 10:50:00 | Our data implicate ZnT2 as a critical mediator of cell death during involution and importantly, that as an initial involution signal, TNFalpha redistributes ZnT2 to lysosomes to activate LCD | 25620235 |
| 2015-09-26 10:35:00 | dephosphorylated S296 was required to target ZnT2 to accumulate Zn in lysosomes | 25808614 |
| 2015-09-05 10:45:00 | Together, these results demonstrate that ZnT2-mediated zinc transport is critical for mammary gland function, suggesting that defects in ZnT2 not only reduce milk zinc concentration but may compromise breast health | 25851903 |
| Type | IDs |
|---|---|
| Synonymous | ZnT-2, Znt2 |
| Gene |
UniProtKB-ID:
ZNT2_MOUSE,
D3Z5N1_MOUSE
UniprotKB:
Q2HJ10,
D3Z5N1
UniParc:
UPI000059E16E,
UPI00001C3161
EMBL:
AL669982,
BC113751
Ensembl:
ENSMUSG00000028836
KO:
mmu:230810
|
| Nucleutide sequences |
EMBL-CDS:
AAI13752.1
Ensembl_TRS:
ENSMUST00000105874,
ENSMUST00000105872,
ENSMUST00000081094
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000101500,
ENSMUSP00000101498,
ENSMUSP00000079875
RefSeq:
NP_001034766.1,
NP_001333507.1,
XP_006538818.1
|
| Others |
UniRef100:
UniRef100_Q2HJ10
UniRef90:
UniRef90_Q2HJ10
UniRef50:
UniRef50_Q9BRI3-2
UniGene:
Mm.358876
CCDS:
CCDS38915.1
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| 1 |
The Pennsylvania State University |
6 |
| 2 |
Penn State Hershey College of Medicine |
4 |
| 3 |
Pennsylvania State University |
3 |
| 4 |
University of Florida |
2 |
| 5 |
Suzuka University of Medical Science |
2 |
| 排名 | 研究人员 | 文献 |
|---|---|---|
| 1 |
Shannon L Kelleher |
12 |
| 2 |
P Carninci |
7 |
| 3 |
Y Hayashizaki |
6 |
| 4 |
K Shibata |
5 |
| 5 |
M Itoh |
5 |