| Type | Description |
|---|---|
| Definition | lysine demethylase 4C |
| Date | Results | Publications |
|---|---|---|
| 2020-10-03 12:55:00 | Wnt-Induced Stabilization of KDM4C Is Required for Wnt/beta-Catenin Target Gene Expression and Glioblastoma Tumorigenesis. | 31888886 |
| 2020-03-28 10:46:00 | Data found that JMJD2C was overexpressed in colorectal cancer (CRC) tumor and metastatic foci, and CRC patients with lower JMJD2C expression had better prognosis. JMJD2C could enhance the metastatic abilities of CRC cells in vitro and in vivo by regulating the histone methylation level of MALAT1 promoter, thereby up-regulating the expression of MALAT1 and enhancing the activity of beta-catenin signaling pathway. | 31665047 |
| 2020-02-29 11:35:00 | data indicate that circKDM4C might have considerable potential as a prognostic biomarker in breast cancer, and support the notion that therapeutic targeting of circKDM4C/miR-548p/PBLD axis may be a promising treatment approach for breast cancer patients | 31406252 |
| 2019-01-26 11:16:00 | CircZMYM2 repressed the expression of its target miR-335-5p. MiR-335-5p attenuated pancreatic cancer development via inhibition of JMJD2C. | 30537731 |
| 2019-01-26 10:09:00 | we have identified KDM4C as a new risk gene shared between systemic vasculitides, consistent with the increasing evidences of the crucial role that the epigenetic mechanisms have in the development of complex immune-mediated conditions. | 29374629 |
| Type | IDs |
|---|---|
| Synonymous | GASC1, JHDM3C, JMJD2C, TDRD14C |
| Gene |
UniProtKB-ID:
KDM4C_HUMAN,
B0QZ60_HUMAN
UniprotKB:
Q9H3R0,
B0QZ60
UniParc:
UPI000199A53B,
UPI000199A53A,
UPI0000367602,
UPI0000211111,
UPI000045890E
EMBL:
AL137020,
AL445592,
AL161443,
AB018323,
AK304032,
AK310439,
BC104859,
AB037901,
AL354707,
BC143571,
AL513412,
BC104861
Ensembl:
ENSG00000107077
KO:
hsa:23081
|
| Nucleutide sequences |
EMBL-CDS:
BAB16102.1,
BAG64946.1,
AAI43572.1,
AAI04862.1,
BAA34500.1,
AAI04860.1
Ensembl_TRS:
ENST00000381306,
ENST00000536108,
ENST00000381309,
ENST00000543771,
ENST00000401787
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000445427,
ENSP00000370710,
ENSP00000440656,
ENSP00000370707,
ENSP00000383990
RefSeq:
NP_001340930.1,
NP_001340927.1,
XP_024303226.1,
XP_011516113.1,
NP_001140168.1,
NP_001291269.1,
XP_016869990.1,
NP_001340929.1,
NP_055876.2,
XP_024303227.1,
NP_001291268.1,
NP_001340926.1,
NP_001291270.1,
NP_001340928.1,
XP_016869991.1,
NP_001140167.1,
XP_016869987.1,
XP_016869993.1,
XP_016869988.1
|
| Others |
UniRef100:
UniRef100_Q9H3R0,
UniRef100_B0QZ60
UniRef90:
UniRef90_A0A2K6LGI0,
UniRef90_Q9H3R0
UniRef50:
UniRef50_A0A2K6LGI0,
UniRef50_Q9H3R0
UniGene:
Hs.709425
CCDS:
CCDS6471.1,
CCDS55286.1,
CCDS55285.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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