| Type | Description |
|---|---|
| Definition | MYC binding protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-09-14 10:29:00 | MYCBP2, a member of the c-myc oncogene family, is a direct functional target of miR-1247. Furthermore, in colorectal cancer patients, MYCBP2 protein levels are associated with miR-1247 levels and survival | 30318507 |
| 2018-09-22 10:37:00 | identification of the neuron-associated E3 ligase MYCBP2 (also known as PHR1) as the apparent single member of a class of RING-linked E3 ligase with esterification activity and intrinsic selectivity for threonine over serine | 29643511 |
| 2016-10-01 11:18:00 | Data indicate an oncogenic role for an Ikaros protein/MYCBP2 protein/proto-oncogene protein c-MYC axis in adult acute lymphoblastic leukemia (ALL), providing a mechanism of target therapies that activate Ikaros in ALL. | 26517351 |
| 2016-01-28 10:17:00 | Arf-bp1 and Pam are novel regulators of circadian gene expression that target Rev-erb alpha for degradation | 20534529 |
| 2015-11-28 10:56:00 | Data show that epithelial-mesenchymal transition (EMT)-transcription factors can be dynamically degraded by an atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 (SPFFbxo45). | 25460509 |
| Type | IDs |
|---|---|
| Synonymous | Myc-bp2, PAM, PHR1, Phr |
| Gene |
UniProtKB-ID:
MYCB2_HUMAN
UniprotKB:
O75592
UniParc:
UPI0001CB7C13,
UPI000D640EBB
EMBL:
AL159154,
AC001226,
CH471093,
AL359257,
AF083244,
AL159158,
AF075587,
BC037971,
AB020723
Ensembl:
ENSG00000005810
KO:
hsa:23077
|
| Nucleutide sequences |
EMBL-CDS:
AAH37971.1,
CAI39758.1,
AAD39842.1,
CAI16842.1,
BAA74939.1,
CAH73736.1,
AAC39928.1,
EAW80565.1,
CAI39759.1
Ensembl_TRS:
ENST00000544440
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000444596
RefSeq:
XP_006719844.1,
XP_011533306.1,
XP_016875943.1,
XP_016875946.1,
XP_016875954.1,
XP_016875949.1,
XP_006719851.1,
XP_006719848.1,
XP_016875955.1,
XP_006719852.1,
XP_006719845.1,
XP_006719843.1,
XP_016875956.1,
XP_006719846.1,
XP_016875947.1,
XP_016875944.1,
XP_006719847.1,
XP_006719850.1,
XP_016875948.1,
XP_016875945.1,
XP_016875957.1,
XP_016875951.1,
XP_011533307.1,
XP_005266356.1,
XP_016875953.1,
NP_055872.4,
XP_016875952.1,
XP_006719842.1,
XP_016875950.1,
XP_006719849.1
|
| Others |
UniRef100:
UniRef100_O75592
UniRef90:
UniRef90_O75592
UniRef50:
UniRef50_O75592
UniGene:
Hs.591221
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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