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230738 Zc3h12a

230738

Zc3h12a

zinc finger CCCH type containing 12A

protein-coding

Mus musculus

基因描述

Type Description
Definition zinc finger CCCH type containing 12A

研究结论

Date Results Publications
2020-12-05 13:04:00 MCPIP1 inhibits Hepatitis B virus replication by destabilizing viral RNA and negatively regulates the virus-induced innate inflammatory responses. 31926181
2020-11-28 13:14:00 Integrative genomics reveal a role for MCPIP1 in adipogenesis and adipocyte metabolism. 31893310
2020-07-11 11:51:00 In peritoneal macrophages, Ang II promoted endoplasmic reticulum stress-dependent macrophage apoptosis. Ang II markedly upregulated the expression of MCPIP1 via activating p38 mitogen-activated protein kinase. 31155290
2020-06-27 12:15:00 Loss of murine epidermal Mcpip1 upregulates transcripts related to inflammation and keratinocyte differentiation. Keratinocyte Mcpip1 function is essential to maintain the integrity of skin in adult mice. Ablation of Mcpip1 in mouse epidermis leads to the development of local and systemic inflammation. 31786670
2020-05-02 10:19:00 by targeting REGNASE-1, CD8(+) T cells are reprogrammed to long-lived effector cells with extensive accumulation, better persistence and robust effector function in tumors; REGNASE-1-deficient CD8(+) T cells show markedly improved therapeutic efficacy against mouse models of melanoma and leukemia 31827283

名称对应

Type IDs
Synonymous BC036563, MCPIP, MCPIP-1, Mcpip1, Reg1
Gene
UniProtKB-ID: ZC12A_MOUSE
UniprotKB: Q5D1E7
UniParc: UPI00000296C5
EMBL: AY920404, AK149698, BC006817, AK161150, AK172357, AK142501, BC036563, AK152196, AL626775
Ensembl: ENSMUSG00000042677
KO: mmu:230738
Nucleutide sequences
EMBL-CDS: BAE29035.1, BAE42965.1, AAH06817.1, AAH36563.1, BAE25089.1, BAE31025.1, BAE36216.1, AAX14018.1
Ensembl_TRS: ENSMUST00000036188
Protein sequencees
Ensembl_PRO: ENSMUSP00000037172
RefSeq: NP_694799.1
Others
UniRef100: UniRef100_Q5D1E7
UniRef90: UniRef90_Q5D1E7
UniRef50: UniRef50_Q5D1E8
UniGene: Mm.402
CCDS: CCDS18638.1

全选

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