| Type | Description |
|---|---|
| Definition | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 10:45:00 | The ubiquitin E3 ligase HECW1 catalyzes TTF1 ubiquitination. | 30849519 |
| 2019-12-14 10:45:00 | Study reported for the first time that HECW1 mRNA levels were negatively correlated with Gd-IgA1 levels and pointed to a new regulatory mechanism of IgA nephropathy that can explain the aberrant glycosylation of IgA1. | 31057023 |
| 2016-08-06 10:31:00 | Ndel1 acts as a novel upstream regulator of the trichoplein-Aurora A pathway to inhibit primary cilia assembly. | 26880200 |
| 2011-08-06 10:37:00 | Ndel1 regulates Dyn2 GTPase activity and impacts GluR1-containing membranes distribution in a manner reminiscent of Dyn2. | 21283621 |
| 2011-02-26 11:19:00 | These findings suggest that the human NEDL1 transgenic mice might develop Amyotrophic lateral sclerosis-like symptoms, showing signs of motor abnormalities, accompanied with significant reduction in muscle strength. | 20976258 |
| Type | IDs |
|---|---|
| Synonymous | NEDL1 |
| Gene |
UniProtKB-ID:
HECW1_HUMAN
UniprotKB:
Q76N89
UniParc:
UPI0000D74C41,
UPI00017A6FD7
EMBL:
AB002320,
AK294918,
AC005537,
BC151227,
AB048365,
AC004455,
AC011738,
AC006365,
AC004692
Ensembl:
ENSG00000002746
KO:
hsa:23072
|
| Nucleutide sequences |
EMBL-CDS:
BAA20780.2,
BAB13352.1,
AAI51228.1,
BAG58003.1
Ensembl_TRS:
ENST00000453890,
ENST00000395891
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000379228,
ENSP00000407774
RefSeq:
NP_001273988.1,
XP_016867373.1,
XP_016867377.1,
XP_016867375.1,
XP_006715734.1,
XP_016867372.1,
XP_016867378.1,
XP_011513522.1,
XP_005249722.1,
XP_011513528.1,
XP_011513524.1,
XP_016867376.1,
XP_011513526.1,
XP_006715736.1,
XP_016867379.1,
XP_016867374.1,
XP_016867371.1,
XP_011513527.2,
XP_011513525.1,
NP_055867.3,
XP_006715733.1
|
| Others |
UniRef100:
UniRef100_Q76N89
UniRef90:
UniRef90_Q76N89
UniRef50:
UniRef50_Q76N89
UniGene:
Hs.164453
CCDS:
CCDS69286.1,
CCDS5469.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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