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230676 Szt2

230676

Szt2

seizure threshold 2

protein-coding

Mus musculus

基因描述

Type Description
Definition seizure threshold 2

研究结论

Date Results Publications
2017-08-19 10:14:00 in mice that lack SZT2, mTORC1 signalling is increased in several tissues, including in neurons in the brain 28199306
2017-08-19 10:14:00 SZT2 has a central role in dictating GATOR-dependent nutrient sensing by promoting lysosomal localization of SZT2-orchestrated GATOR complex, and reveal an unexpected function of lysosome-located GATOR2 in suppressing mTORC1 signalling through SESN recruitment 28199315
2010-01-21 00:00:00 While the biological function of Szt2 remains unknown, its high conservation, unique structure and effect on seizure threshold suggest that it serves an important role in the central nervous system. 19624305

名称对应

Type IDs
Synonymous 6430407N22, TIGR
Gene
UniProtKB-ID: SZT2_MOUSE
UniprotKB: A2A9C3
UniParc: UPI000059E0A8, UPI0001E24F47
EMBL: BC059842, FJ998170, AL627212, GU433214, BC052935
Ensembl: ENSMUSG00000033253
KO: mmu:230676
Nucleutide sequences
EMBL-CDS: AAH52935.1, ACS91341.1, AAH59842.2
Ensembl_TRS: ENSMUST00000075406
Protein sequencees
Ensembl_PRO: ENSMUSP00000074862
RefSeq: NP_937813.3, XP_036019929.1
Others
UniRef100: UniRef100_A2A9C3
UniRef90: UniRef90_Q5T011
UniRef50: UniRef50_Q5T011
UniGene: Mm.415218
CCDS: CCDS51283.1

全选

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研究热度

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