| Type | Description |
|---|---|
| Definition | lysine (K)-specific demethylase 4A |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 12:49:00 | KDM4 knockdown resulted in the down-regulation of miR-29 expression. | 31014673 |
| 2020-06-20 10:41:00 | KDM4A inhibition as a potential therapeutic target for treating metabolic disorders. | 31515577 |
| 2020-04-25 12:24:00 | KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes. | 32231309 |
| 2020-02-01 12:34:00 | The knockout of the KDM4 demethylases leads to accumulation of H3K9me3 on transcription start sites and the corresponding downregulation of expression of several genes in hematopoietic stem cell. | 31434704 |
| 2018-01-20 11:10:00 | Jmjd2 class demethylases are critical epigenetic regulators involved in etiopathology of depression and related disorders. | 27711046 |
| Type | IDs |
|---|---|
| Synonymous | D4Ertd222e, JHDM3A, Jmjd2, Jmjd2a, mKIAA0677 |
| Gene |
UniProtKB-ID:
KDM4A_MOUSE,
A2A8L9_MOUSE
UniprotKB:
Q8BW72,
A2A8L9
UniParc:
UPI000217CB40,
UPI0000193395,
UPI00001C3097
EMBL:
AK145066,
AK145947,
BC028866,
AK129187,
AL626764,
AK054095,
AK136085
Ensembl:
ENSMUSG00000033326
KO:
mmu:230674
|
| Nucleutide sequences |
EMBL-CDS:
AAH28866.1,
BAC97997.1,
BAE26217.1,
BAE22812.1,
BAE26776.1,
BAC35653.1
Ensembl_TRS:
ENSMUST00000106403,
ENSMUST00000106406,
ENSMUST00000097911,
ENSMUST00000050288
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000095524,
ENSMUSP00000102011,
ENSMUSP00000102014,
ENSMUSP00000062910
RefSeq:
XP_006503073.1,
NP_001155295.1,
NP_759014.2
|
| Others |
UniRef100:
UniRef100_Q8BW72,
UniRef100_A2A8L9
UniRef90:
UniRef90_Q8BW72
UniRef50:
UniRef50_O75164
UniGene:
Mm.234234
CCDS:
CCDS51282.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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