| Type | Description |
|---|---|
| Definition | WAPL cohesin release factor |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 14:05:00 | WAPL-Dependent Repair of Damaged Forks Underlies Oncogene-Induced Loss of Cohesion. | 32084359 |
| 2020-02-29 10:07:00 | Absolute copy numbers and dynamics of cohesin, CTCF, NIPBL, WAPL and sororin were measured by mass spectrometry, fluorescence-correlation spectroscopy and fluorescence recovery after photobleaching in HeLa cells. | 31204999 |
| 2020-01-11 11:36:00 | In p53-compromised cells we find that lethal replication stress confers WAPL-dependent centromere cohesion defects that maintain spindle assembly checkpoint-dependent mitotic arrest in the same cell cycle. | 31530811 |
| 2019-12-07 11:45:00 | Rec8-Stag3 cohesin is shown to be susceptible to Wapl-dependent ring opening and sororin-mediated protection. | 29724914 |
| 2019-10-19 10:03:00 | We provide evidence that the underlying mechanism involves the viral NS3/4 protease and the cohesin regulator, WAPL | 30698808 |
| Type | IDs |
|---|---|
| Synonymous | FOE, KIAA0261, WAPAL |
| Gene |
UniProtKB-ID:
WAPL_HUMAN,
B2RTX8_HUMAN,
A8K273_HUMAN
UniprotKB:
Q7Z5K2,
B2RTX8,
A8K273
UniParc:
UPI0000458B0A,
UPI00001AE41A,
UPI00015DA4E0,
UPI0001747A82,
UPI0000074436
EMBL:
BC150269,
AB065003,
AL844892,
AK290138,
AF479418,
AL731569,
BC140858,
D87450,
CH471142
Ensembl:
ENSG00000062650
KO:
hsa:23063
|
| Nucleutide sequences |
EMBL-CDS:
EAW80336.1,
BAA13391.1,
BAC78631.1,
AAO14651.1,
AAI50270.1,
AAI40859.1,
BAF82827.1
Ensembl_TRS:
ENST00000618527,
ENST00000298767
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000298767,
ENSP00000481451
RefSeq:
XP_011537850.1,
XP_016871468.1,
XP_016871470.1,
NP_001305257.1,
XP_016871469.1,
NP_055860.1
|
| Others |
UniRef100:
UniRef100_Q7Z5K2,
UniRef100_A8K273,
UniRef100_B2RTX8
UniRef90:
UniRef90_A8K273,
UniRef90_B2RTX8,
UniRef90_Q7Z5K2
UniRef50:
UniRef50_A0A670ZSW3,
UniRef50_Q7Z5K2
UniGene:
Hs.203099,
Hs.714876
CCDS:
CCDS7375.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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