| Type | Description |
|---|---|
| Definition | SMG1 nonsense mediated mRNA decay associated PI3K related kinase |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:30:00 | Structure of substrate-bound SMG1-8-9 kinase complex reveals molecular basis for phosphorylation specificity. | 32469312 |
| 2020-09-19 16:25:00 | Cryo-EM structure of SMG1-SMG8-SMG9 complex. | 31729466 |
| 2020-08-29 12:46:00 | MicroRNA-18a promotes cancer progression through SMG1 suppression and mTOR pathway activation in nasopharyngeal carcinoma. | 31659158 |
| 2020-03-07 11:39:00 | SMG1 variants c.4249A>G and c.103G>A are associated with pancreatic cancer in large study | 31469826 |
| 2020-02-29 11:09:00 | This study reports the 3.45-A resolution cryo-EM structure of human SMG1-SMG8-SMG9, a phosphatidylinositol-3-kinase (PI(3)K)-related protein kinase (PIKK) complex central to messenger RNA surveillance. | 31792449 |
| Type | IDs |
|---|---|
| Synonymous | 61E3.4, ATX, LIP |
| Gene |
UniProtKB-ID:
SMG1_HUMAN
UniprotKB:
Q96Q15
UniParc:
UPI000059D32A,
UPI0000070116,
UPI00004F8E22,
UPI000059D32C
EMBL:
AB061371,
AB007881,
AC092287,
AY014957,
AF186377,
AF395444,
U32581
Ensembl:
ENSG00000157106
KO:
hsa:23049
|
| Nucleutide sequences |
EMBL-CDS:
BAB70696.1,
AAM73708.1,
AAK58892.1,
BAA24851.2,
AAA86535.2,
AAK00511.1
Ensembl_TRS:
ENST00000446231
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000402515
RefSeq:
XP_005255241.1,
NP_055907.3,
XP_024305967.1,
XP_011544071.1,
XP_005255239.1,
XP_016878556.1,
XP_011544072.1,
XP_024305966.1,
XP_005255240.1,
XP_016878555.1
|
| Others |
UniRef100:
UniRef100_Q96Q15
UniRef90:
UniRef90_Q96Q15
UniRef50:
UniRef50_Q96Q15
UniGene:
Hs.460179
CCDS:
CCDS45430.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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