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230484 Usp1

230484

Usp1

ubiquitin specific peptidase 1

protein-coding

Mus musculus

基因描述

Type Description
Definition ubiquitin specific peptidase 1

研究结论

Date Results Publications
2016-12-17 10:44:00 our results strongly suggest that Usp1 is involved in the regulation of centrosome duplication, at least in part via ID1, and Usp1 may exert its oncogenic activity, partially through inducing centrosome abnormality. 26822809
2016-06-28 10:40:00 Data suggest Usp1 down-regulation by autocleavage is critical for Usp1 to exert role in DNA interstrand crosslink repair; Usp1 role is de-ubiquitination of Fancd2 (Fanconi anemia complementation group D2) and Pcna (proliferating cell nuclear antigen). 26783108
2013-12-28 10:44:00 Homozygous Uaf1(-/-) embryos died at embryonic day 7.5 (E7.5). These mutant embryos were small and developmentally retarded. 24001775
2013-02-23 11:24:00 Autocleaved Usp1 remains a deubiquitylase because its fragments remain associated with Uaf1, an enhancer of Usp1 activity, until the C-terminal fragment is selectively destroyed by the Arg/N-end rule pathway. 23159736
2010-11-13 10:40:00 Bone marrow from Fancd2-/- mice and Usp1-/- mice exhibited marked hematopoietic defects. 20506303

名称对应

Type IDs
Gene
UniProtKB-ID: UBP1_MOUSE
UniprotKB: Q8BJQ2
UniParc: UPI00000EB68B
EMBL: BC018179, AL627349, BC020007, AK080882
Ensembl: ENSMUSG00000028560
KO: mmu:230484
Nucleutide sequences
EMBL-CDS: AAH18179.1, BAC38059.1, AAH20007.1
Ensembl_TRS: ENSMUST00000091358, ENSMUST00000030289
Protein sequencees
Ensembl_PRO: ENSMUSP00000030289, ENSMUSP00000088917
RefSeq: NP_666256.2, NP_001288343.1, NP_001343353.1
Others
UniRef100: UniRef100_Q8BJQ2
UniRef90: UniRef90_Q8BJQ2
UniRef50: UniRef50_O94782
UniGene: Mm.371692
CCDS: CCDS18381.1

全选

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