| Type | Description |
|---|---|
| Definition | formin binding protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-23 13:02:00 | High formin binding protein 17 (FBP17) expression indicates poor differentiation and invasiveness of ductal carcinomas. | 32665637 |
| 2020-04-11 11:10:00 | Study shows that plasma membrane (PM) mechanoadaptation is controlled by a tension-sensing pathway composed of c-Abl tyrosine kinase and membrane curvature regulator FBP17. FBP17 is recruited to caveolae to induce the formation of caveolar rosettes. FBP17 deficient cells have reduced rosette density, lack PM tension buffering capacity under osmotic shock, and cannot adapt to mechanical strain. | 31862885 |
| 2019-05-11 12:58:00 | FBP17 and CIP4 prime the membrane of resting cells for fast endophilin-mediated endocytosis by recruiting the 5'-lipid phosphatase SHIP2 and lamellipodin to mediate the local production of phosphatidylinositol-3,4-bisphosphate and endophilin pre-enrichment. | 30061681 |
| 2018-09-01 11:58:00 | Results suggest that FBP17 is highly expressed in breast cancer cells and facilitates the invasion of breast cancer cells. | 29651632 |
| 2015-09-05 10:48:00 | FBP17 is the local activator of actin polymerization that is inhibited by PM tension in the feedback loop that regulates cell migration. | 25938814 |
| Type | IDs |
|---|---|
| Synonymous | FBP17 |
| Gene |
UniProtKB-ID:
FNBP1_HUMAN,
B7ZL13_HUMAN,
B7ZL14_HUMAN
UniprotKB:
Q96RU3,
B7ZL13,
B7ZL14
UniParc:
UPI000189A79B,
UPI0000E825A9,
UPI000189A79A,
UPI0000E825A8,
UPI000022408C,
UPI000189A799,
UPI00002119B9
EMBL:
AF265550,
BC143515,
BC143513,
BC062463,
AB011126,
AK023681,
BC143514,
AL158207,
AK000975,
BC101755,
AL136141
Ensembl:
ENSG00000187239
KO:
hsa:23048
|
| Nucleutide sequences |
EMBL-CDS:
AAH62463.1,
BAA91451.1,
AAK49824.1,
AAI43514.1,
BAA25480.1,
AAI01756.1,
BAB14638.1,
AAI43515.1,
AAI43516.1
Ensembl_TRS:
ENST00000446176,
ENST00000420781,
ENST00000355681,
ENST00000443566
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000347907,
ENSP00000413625,
ENSP00000407548,
ENSP00000389117
RefSeq:
XP_005251890.1,
XP_005251883.1,
XP_005251889.1,
XP_005251884.1,
XP_005251877.1,
XP_005251888.1,
XP_016869977.1,
XP_005251872.1,
XP_005251880.1,
XP_005251879.1,
XP_005251885.1,
XP_016869983.1,
XP_024303225.1,
NP_055848.1,
XP_011516703.1,
XP_016869981.1,
XP_005251878.1,
XP_016869982.1,
XP_016869980.1,
XP_011516701.1,
XP_005251882.1,
XP_016869979.1,
XP_011516704.1,
XP_011516702.1,
XP_006717079.1,
XP_005251881.1,
XP_016869978.1,
XP_016869976.1,
XP_005251891.1,
XP_005251887.1,
NP_001350684.1
|
| Others |
UniRef100:
UniRef100_Q96RU3,
UniRef100_B7ZL14,
UniRef100_B7ZL13
UniRef90:
UniRef90_Q96RU3-2,
UniRef90_Q96RU3
UniRef50:
UniRef50_Q96RU3
UniGene:
Hs.189409
CCDS:
CCDS87699.1,
CCDS48040.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员