| Type | Description |
|---|---|
| Definition | TRAF2 and NCK interacting kinase |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:45:00 | Effect of TNIK upregulation on JQ1-resistant human colorectal cancer HCT116 cells. | 32828291 |
| 2020-01-18 10:58:00 | We also show that the TNIK protein isoforms including/excluding exon 15 differently regulate cell spreading in non-neuronal cells and neuritogenesis in primary cortical neurons. Our data suggest a complex regulation between the ubiquitous TDP-43 and the neuron-specific NOVA-1 splicing factors in the brain that may help better understand the pathobiology of both neurodegenerative diseases and schizophrenia. | 31382054 |
| 2019-04-06 11:51:00 | Genome-wide association study on the etiology of adolescent idiopathic scoliosis using samples from more than 5 000 patients and 6 000 normal controls showed two genes: LBX1-AS1 on 10q24.32 and TNIK on 3q26.2 highly related to AIS initiation and progression [review] | 30107698 |
| 2018-09-22 10:15:00 | TNIK is required for the tumour-initiating function of colorectal cancer stem cells. Its inhibition is a promising therapeutic approach. | 27562646 |
| 2018-04-14 10:19:00 | Results indicate that Traf2- and Nck-interacting kinase (TNIK) is involved in the interleukin-6-dependent proliferation of multiple myeloma cells. | 28467797 |
| Type | IDs |
|---|---|
| Synonymous | MRT54 |
| Gene |
UniProtKB-ID:
TNIK_HUMAN
UniprotKB:
Q9UKE5
UniParc:
UPI000002B586,
UPI000002B588,
UPI000002B587,
UPI000002B585,
UPI000002B589,
UPI000002B58B,
UPI000003ABDF,
UPI000002B58A
EMBL:
AB011123,
AF172270,
AF172266,
AK291056,
AF172269,
AF172267,
AF172265,
AC137517,
AC092919,
AC078793,
AF172271,
BC150256,
CH471052,
AC026315,
AF172268,
AF172264,
BC019081
Ensembl:
ENSG00000154310
KO:
hsa:23043
|
| Nucleutide sequences |
EMBL-CDS:
AAF03784.1,
AAF03783.1,
AAI50257.1,
EAW78489.1,
AAF03788.1,
AAF03789.1,
AAF03787.1,
EAW78493.1,
BAF83745.1,
AAF03786.1,
EAW78484.1,
AAH19081.2,
EAW78492.1,
AAF03782.1,
BAA25477.2,
AAF03785.1
Ensembl_TRS:
ENST00000470834,
ENST00000284483,
ENST00000341852,
ENST00000460047,
ENST00000357327,
ENST00000436636,
ENST00000488470,
ENST00000475336
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000349880,
ENSP00000418916,
ENSP00000419990,
ENSP00000418378,
ENSP00000345352,
ENSP00000418156,
ENSP00000284483,
ENSP00000399511
RefSeq:
NP_001155034.1,
NP_001155037.1,
NP_001155038.1,
NP_001155036.1,
NP_001155032.1,
NP_055843.1,
NP_001155035.1,
NP_001155033.1
|
| Others |
UniRef100:
UniRef100_Q9UKE5
UniRef90:
UniRef90_Q9UKE5
UniRef50:
UniRef50_Q9UKE5
UniGene:
Hs.34024
CCDS:
CCDS54678.1,
CCDS54675.1,
CCDS54676.1,
CCDS46956.1,
CCDS54673.1,
CCDS54679.1,
CCDS54674.1,
CCDS54677.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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