| Type | Description |
|---|---|
| Definition | ubiquitin specific peptidase 33 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:35:00 | USP33 regulates c-Met expression by deubiquitinating SP1 to facilitate metastasis in hepatocellular carcinoma. | 32835698 |
| 2019-06-23 00:16:00 | Our study reveals the inhibitory function of Slit-Robo signalling in gastric cancer (GC) and uncovers a role of USP33 in suppressing cancer cell migration and epithelial-mesenchymal transition by enhancing Slit2-Robo1 signalling. USP33 represents a feasible choice as a prognostic biomarker for GC. | 30896071 |
| 2018-10-06 12:08:00 | USP33 was downregulated in gastric adenocarcinoma. | 29802710 |
| 2018-05-19 11:24:00 | Fluorescence-activated cell sorting experiment found no significant effect of USP33 on cell cycle, whereas the apoptotic caspase proteins were activated by USP33-overexpression and the interaction between USP33 and Robo1 protein was identified, and knockdown of Robo1 enhancing the oncogenic effect upon USP33-knockdown, suggesting that USP33 may inhibit tumor progression through Robo1 signaling. | 29533940 |
| 2018-02-24 11:37:00 | USP33 may indirectly regulate the degradation and recycling of CXCR4 through deubiquitinating beta-arrestin2, promoting colorectal tumor cell metastasis. | 27835898 |
| Type | IDs |
|---|---|
| Synonymous | VDU1 |
| Gene |
UniProtKB-ID:
UBP33_HUMAN
UniprotKB:
Q8TEY7
UniParc:
UPI000006DC34,
UPI000034ECB7,
UPI000022ABDA
EMBL:
AB029020,
AF383172,
BC016663,
AC114487,
AF383173,
AK022864
Ensembl:
ENSG00000077254
KO:
hsa:23032
|
| Nucleutide sequences |
EMBL-CDS:
BAB14279.1,
AAL78314.1,
AAH16663.1,
AAL78315.1,
BAA83049.1
Ensembl_TRS:
ENST00000370793,
ENST00000357428,
ENST00000370794,
ENST00000370792
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000350009,
ENSP00000359828,
ENSP00000359829,
ENSP00000359830
RefSeq:
NP_963920.1,
NP_001364366.1,
NP_001364368.1,
NP_001364362.1,
NP_055832.3,
XP_011539358.1,
NP_001364359.1,
XP_016856218.1,
NP_001364361.1,
NP_001364360.1,
NP_001364365.1,
NP_001364363.1,
NP_963918.1,
NP_001364367.1,
NP_001364364.1
|
| Others |
UniRef100:
UniRef100_Q8TEY7
UniRef90:
UniRef90_Q8TEY7
UniRef50:
UniRef50_Q8TEY7
UniGene:
Hs.480597
CCDS:
CCDS678.1,
CCDS679.1,
CCDS680.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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