| Type | Description |
|---|---|
| Definition | CCR4-NOT transcription complex subunit 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 15:58:00 | ARE-binding protein ZFP36L1 interacts with CNOT1 to directly repress translation via a deadenylation-independent mechanism. | 32311426 |
| 2020-10-24 14:10:00 | Variants in CNOT1, a Central Component of the CCR4-NOT Complex Involved in Gene Expression and RNA and Protein Stability, Cause Neurodevelopmental Delay. | 32553196 |
| 2020-08-15 19:07:00 | A Quantitative Genetic Interaction Map of HIV Infection. | 32084337 |
| 2020-03-21 10:35:00 | Through its interaction with the Ccr4-Not complex, eIF4A2 represses mRNAs at translation initiation. | 31791371 |
| 2020-02-08 10:30:00 | CNOT1 Mutation is associated with a Novel Syndrome of Pancreatic Agenesis and Holoprosencephaly through Impaired Pancreatic and Neurological Development. | 31006513 |
| Type | IDs |
|---|---|
| Synonymous | AD-005, CDC39, NOT1, NOT1H |
| Gene |
UniProtKB-ID:
CNOT1_HUMAN
UniprotKB:
A5YKK6
UniParc:
UPI00001AEF72,
UPI000162779A,
UPI000059D39B,
UPI00001FF2F6
EMBL:
CR749237,
AC010287,
BX537840,
AL117492,
BC040523,
BC024317,
AC009118,
AB023224,
AF110778,
EF553522,
BC000779
Ensembl:
ENSG00000125107
KO:
hsa:23019
|
| Nucleutide sequences |
EMBL-CDS:
AAH00779.2,
CAD97851.1,
AAH24317.1,
CAB55960.1,
ABQ66268.1,
CAH18093.1,
BAA76851.2,
AAH40523.1,
AAF14861.1
Gene_ORFName:
AD-005
Ensembl_TRS:
ENST00000567188,
ENST00000317147,
ENST00000569240,
ENST00000441024
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000413113,
ENSP00000456649,
ENSP00000455635,
ENSP00000320949
RefSeq:
NP_057368.3,
NP_001252541.1,
NP_996882.1
|
| Others |
UniRef100:
UniRef100_A5YKK6
UniRef90:
UniRef90_A5YKK6
UniRef50:
UniRef50_A5YKK6
UniGene:
Hs.460923,
Hs.731691
CCDS:
CCDS58468.1,
CCDS45501.1,
CCDS10799.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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