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23012 STK38L

23012

STK38L

serine/threonine kinase 38 like

protein-coding

Homo sapiens

基因描述

Type Description
Definition serine/threonine kinase 38 like

研究结论

Date Results Publications
2020-06-27 12:40:00 The results demonstrate that NDR2 is a reversible acetylated kinase regulated by SIRT1 and p300/CBP. 31427083
2020-04-11 10:19:00 NDR2 positively regulated an antiviral innate immune response in a kinase activity-independent manner. NDR2 interacts with RIG-I and promotes TRIM25-mediated RIG-I ubiquitination, which is required for downstream signaling activation and type I IFN production. 30775439
2020-01-25 12:36:00 Study identified rs10842893 as a novel independent SNP in the gene STK38L that was significantly associated with glioma risk in Chinese population, and furthermore confirmed previously reported associations of rs498872 and rs6010620 with glioma risk in European descent population and Chinese Han population. 30714141
2019-07-22 09:20:00 This study shows that STK38L is co-amplified with oncogenic KRAS in pancreatic cancer cell lines, where it regulates LATS2 gene expression. 29108249
2019-05-04 10:47:00 These results suggest that NDR2 may play important roles in IL-17-associated inflammation by promoting Smurf1-mediated MEKK2 ubiquitination and degradation. 30504095

名称对应

Type IDs
Synonymous NDR2
Gene
UniProtKB-ID: ST38L_HUMAN
UniprotKB: Q9Y2H1
UniParc: UPI00017A870B, UPI0000035B4A
EMBL: AB023182, AC092827, AC092829, BC028603, CH471094, AK291055, AK304755
Ensembl: ENSG00000211455
KO: hsa:23012
Nucleutide sequences
EMBL-CDS: BAA76809.2, BAF83744.1, AAH28603.1, EAW96549.1, BAG65510.1
Ensembl_TRS: ENST00000389032
Protein sequencees
Ensembl_PRO: ENSP00000373684
RefSeq: NP_055815.1, XP_006719122.1, XP_024304659.1, XP_005253399.1, XP_024304662.1, XP_024304664.1, XP_024304657.1, XP_011518915.1, XP_024304663.1, XP_024304661.1, XP_024304658.1, XP_024304665.1, XP_024304660.1, XP_006719121.1
Others
UniRef100: UniRef100_Q9Y2H1
UniRef90: UniRef90_Q9Y2H1
UniRef50: UniRef50_Q15208
UniGene: Hs.184523
CCDS: CCDS31761.1

全选

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