| Type | Description |
|---|---|
| Definition | ATP binding cassette subfamily F member 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-02 12:05:00 | The ATP-binding cassette transporter ABCF1 is a hepatic oncofetal protein that promotes chemoresistance, epithelial mesenchymal transformation and cancer stemness in hepatocellular carcinoma cells. | 31100412 |
| 2019-12-21 11:34:00 | The combined assessment of IGF2BP3 and ABCF1 predicts recurrence in Ewing sarcoma patients. | 29703820 |
| 2019-09-21 12:33:00 | Study solves the crystal structure of an ATP-bound wild-type human ABCF1 at 2.3-A resolution. The comparative studies indicate that the structure is in a pre-activation intermediate conformation. This conformation is stabilized by the interaction between ATP and protein suggesting that this conformation is an important step in the activation of ABCF1. | 30017566 |
| 2018-07-21 11:48:00 | The high copy number variant in the ABCF1 gene was the strongest risk factor for gout. | 28405828 |
| 2016-05-21 12:45:00 | ABCF1 extrinsically regulates retinal pigment epithelial cell phagocytosis of shed photoreceptor outer segments. | 25904329 |
| Type | IDs |
|---|---|
| Synonymous | ABC27, ABC50 |
| Gene |
UniProtKB-ID:
ABCF1_HUMAN,
A0A1U9X609_HUMAN,
Q2L6I2_HUMAN
UniprotKB:
Q8NE71,
A0A1U9X609,
Q2L6I2
UniParc:
UPI000000D73B,
UPI0000141876
EMBL:
BX927220,
BA000025,
AL832430,
AF027302,
CR753328,
CR847863,
BC034488,
CR388372,
KY500134,
AB202093,
BC112923,
AL662800,
BX000357,
CR759778,
AL662825,
AB103602,
CH471081,
BX248518,
AB088096,
KY500135,
BX119957
Ensembl:
ENSG00000225989,
ENSG00000206490,
ENSG00000232169,
ENSG00000236342,
ENSG00000236149,
ENSG00000204574,
ENSG00000231129
KO:
hsa:23
|
| Nucleutide sequences |
EMBL-CDS:
CAH10648.1,
BAC54928.1,
BAB63325.1,
AAH34488.1,
AAI12924.1,
AAC70891.1,
AQY76225.1,
AQY76226.1,
EAX03300.1,
BAF31263.1,
BAE78612.1,
EAX03301.1
Gene_ORFName:
hCG_26012
Ensembl_TRS:
ENST00000326195,
ENST00000452530,
ENST00000421042,
ENST00000412443,
ENST00000426219,
ENST00000448939,
ENST00000457078,
ENST00000457111,
ENST00000383587,
ENST00000423247,
ENST00000376545,
ENST00000383588,
ENST00000420257,
ENST00000419893
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000365728,
ENSP00000389065,
ENSP00000373082,
ENSP00000391102,
ENSP00000404726,
ENSP00000389472,
ENSP00000403526,
ENSP00000413319,
ENSP00000412553,
ENSP00000414373,
ENSP00000393143,
ENSP00000411327,
ENSP00000373081,
ENSP00000313603
RefSeq:
NP_001081.1,
NP_001020262.1
|
| Others |
UniRef100:
UniRef100_Q8NE71,
UniRef100_Q2L6I2
UniRef90:
UniRef90_Q7YR37,
UniRef90_Q8NE71
UniRef50:
UniRef50_Q8NE71,
UniRef50_Q7YR37
UniGene:
Hs.655285
CCDS:
CCDS34380.1,
CCDS34381.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员