| Type | Description |
|---|---|
| Definition | centrosomal protein 152 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-15 19:08:00 | Requirement of the Cep57-Cep63 Interaction for Proper Cep152 Recruitment and Centriole Duplication. | 32152252 |
| 2019-04-06 11:35:00 | Study shows that Cep63 and Cep152 cooperatively generate a heterotetrameric alpha-helical bundle that functions in conjunction with its neighboring hydrophobic motifs to self-assemble into a higher-order cylindrical architecture capable of recruiting downstream components, including Plk4, a key regulator for centriole duplication. Mutations disrupting the self-assembly abrogate Plk4-mediated centriole duplication. | 30858376 |
| 2018-10-27 11:55:00 | results demonstrate the different roles of Cep192 and Cep152 in MTOC remodeling and a novel regulatory mechanism during meiotic spindle formation in mouse oocytes. | 28970258 |
| 2014-10-11 10:50:00 | Plk4 is intricately regulated in time and space through ordered interactions with two distinct scaffolds, Cep192 and Cep152, and a failure in this process may lead to human cancer. | 24997597 |
| 2014-04-05 11:24:00 | both mouse and human Cep63 and Cep152 cooperate to ensure efficient centriole duplication by promoting the accumulation of essential centriole duplication factors upstream of SAS-6 recruitment and procentriole formation. | 23936128 |
| Type | IDs |
|---|---|
| Synonymous | MCPH4, MCPH9, SCKL5 |
| Gene |
UniProtKB-ID:
CE152_HUMAN,
Q3B7A2_HUMAN
UniprotKB:
O94986,
Q3B7A2
UniParc:
UPI00005D3A44,
UPI00002378C4,
UPI0000DA58CC,
UPI00001C1F8A,
UPI00001D777C
EMBL:
BC069186,
AC084757,
BC117182,
AB020719,
BC107721,
AC022084,
AC012379
Ensembl:
ENSG00000103995
KO:
hsa:22995
|
| Nucleutide sequences |
EMBL-CDS:
BAA74935.1,
AAH69186.1,
AAI17183.1,
AAI07722.1
Ensembl_TRS:
ENST00000325747,
ENST00000399334,
ENST00000380950
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000370337,
ENSP00000382271,
ENSP00000321000
RefSeq:
XP_011519675.1,
XP_024305643.1,
XP_011519677.1,
XP_011519683.1,
NP_001181927.1,
NP_055800.2,
XP_011519676.1,
XP_011519680.1,
XP_016877504.1,
XP_006720500.1,
XP_016877505.1,
XP_011519681.1
|
| Others |
UniRef100:
UniRef100_Q3B7A2,
UniRef100_O94986
UniRef90:
UniRef90_Q3B7A2,
UniRef90_O94986
UniRef50:
UniRef50_Q3B7A2,
UniRef50_O94986
UniGene:
Hs.443005,
Hs.597323
CCDS:
CCDS58361.1,
CCDS42033.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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