例如:"NBL1", "4681", "drought"
收藏
22994 CEP131

22994

CEP131

centrosomal protein 131

protein-coding

Homo sapiens

基因描述

Type Description
Definition centrosomal protein 131

研究结论

Date Results Publications
2020-08-01 11:07:00 These findings demonstrate that Cep131 is a novel substrate of Plk4, and that phosphorylation or dysregulated Cep131 overexpression promotes Plk4 stabilization and therefore centrosome amplification, establishing a perspective in understanding a relationship between centrosome amplification and cancer development. 31358734
2019-10-19 12:12:00 PLK4 phosphorylates CEP131 at Ser-78 to maintain centriolar satellite integrity. 30804208
2019-03-23 12:19:00 RNA of AZI1 functions as the "initiator" RNA to induce TMPRSS2-ERG fusion. 30538195
2017-11-18 12:28:00 CEP131 serves as a potential prognostic biomarker in HCC 28694105
2016-07-02 11:58:00 CEP131 is the key regulatory target of MK2 and 14-3-3 in centriolar satellite remodeling. 26616734

名称对应

Type IDs
Synonymous AZ1, AZI1, ZA1
Gene
UniProtKB-ID: CP131_HUMAN, I3L2J8_HUMAN
UniprotKB: Q9UPN4, I3L2J8
UniParc: UPI00002017B6, UPI00025A2E11, UPI0000D623A9, UPI00001C1FC8
EMBL: AB029041, BC136580, AC027601, BC011615
Ensembl: ENSG00000141577
KO: hsa:22994
Nucleutide sequences
EMBL-CDS: AAH11615.2, AAI36581.1, BAA83070.1
Ensembl_TRS: ENST00000450824, ENST00000374782, ENST00000269392, ENST00000575907
Protein sequencees
Ensembl_PRO: ENSP00000363914, ENSP00000269392, ENSP00000393583, ENSP00000459733
RefSeq: NP_055799.2, XP_011522855.1, XP_011522849.1, XP_011522854.1, NP_001009811.2, XP_011522852.1, NP_001306157.1, XP_016879858.1, XP_011522850.1, XP_011522853.1, NP_001306158.1, XP_011522857.1
Others
UniRef100: UniRef100_Q9UPN4, UniRef100_I3L2J8
UniRef90: UniRef90_Q9UPN4
UniRef50: UniRef50_Q9UPN4
UniGene: Hs.514578
CCDS: CCDS45808.1, CCDS32764.1, CCDS82215.1

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员