| Type | Description |
|---|---|
| Definition | RAP1, GTP-GDP dissociation stimulator 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-09-28 11:52:00 | Apoe(-/-) SmgGDS(+/-) mice showed significantly higher levels of oxidative stress, matrix metalloproteinases, and inflammatory cell migration in the ascending aorta compared with Apoe(-/-) mice. local delivery of the SmgGDS gene construct reversed the dilation of the ascending aorta in Apoe(-/-) SmgGDS(+/-) mice. | 29921611 |
| 2018-03-24 10:44:00 | Simulated microgravity activates Cdc42 via Rap1GDS1 to promote vascular branch morphogenesis. | 29145128 |
| 2016-10-22 12:17:00 | results indicate that statins selectively up-regulate SmgGDS in endothelial cells, for which the beta1-integrin/Akt1 pathway may be involved, demonstrating the novel aspects of the pleiotropic effects of statins | 26598509 |
| 2013-08-31 12:04:00 | These results indicate that statins exert their pleiotropic effects through SmgGDS upregulation with a resultant Rac1 degradation and reduced oxidative stress in animals and humans. | 23640485 |
| Type | IDs |
|---|---|
| Synonymous | BC011279, GDS1 |
| Gene |
UniProtKB-ID:
E9Q912_MOUSE,
Q3TPS9_MOUSE,
E9Q6Q4_MOUSE,
Q3TU36_MOUSE
UniprotKB:
E9Q912,
Q3TPS9,
E9Q6Q4,
Q3TU36
UniParc:
UPI00001EFFF1,
UPI0000D7D6F1,
UPI00005B1CC2,
UPI00005B202C
EMBL:
AC119881,
AC113307,
AK164159,
AK160989,
AC110574
Ensembl:
ENSMUSG00000028149
KO:
mmu:229877
|
| Nucleutide sequences |
EMBL-CDS:
BAE37656.1,
BAE36135.1
Ensembl_TRS:
ENSMUST00000098574,
ENSMUST00000029796,
ENSMUST00000196280
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000096173,
ENSMUSP00000029796,
ENSMUSP00000143181
RefSeq:
NP_001035780.1,
NP_001273688.1,
NP_001343317.1,
XP_036018980.1,
XP_036018981.1,
XP_030108462.1,
XP_006501492.1,
NP_663519.2,
XP_006501491.1,
XP_036018979.1
|
| Others |
UniRef100:
UniRef100_E9Q912,
UniRef100_Q3TPS9,
UniRef100_E9Q6Q4,
UniRef100_Q3TU36
UniRef90:
UniRef90_E9Q912,
UniRef90_Q3TU36
UniRef50:
UniRef50_E9Q912,
UniRef50_P52306
UniGene:
Mm.28893
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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