| Type | Description |
|---|---|
| Definition | synaptic vesicle glycoprotein 2C |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:29:00 | Identification of Risk Loci for Parkinson Disease in Asians and Comparison of Risk Between Asians and Europeans: A Genome-Wide Association Study. | 32310270 |
| 2018-04-28 10:45:00 | These data establish SV2C as a mediator of dopamine neuron function and suggest that SV2C disruption is a unique feature of PD that likely contributes to dopaminergic dysfunction. | 28246328 |
| 2017-06-10 12:30:00 | N-linked glycosylation of SV2C is required for binding and uptake of botulinum neurotoxin A. | 27294781 |
| 2015-08-29 11:27:00 | Studies indicate that botulinum neurotoxins (BoNTs) in complex with its protein receptor, synaptic vesicle glycoprotein 2 (SV2) family member C represented a major advance for the detailed molecular understanding of BoNT-host cell receptor interactions. | 25282537 |
| 2014-11-08 13:40:00 | A genetic variant in SV2C predicted clinically relevant bevacizumab-induced hypertension in two independent, randomised phase III trials. | 25117820 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
SV2C_HUMAN,
B3KT41_HUMAN
UniprotKB:
Q496J9,
B3KT41
UniParc:
UPI000011DDBB,
UPI0000140DB1
EMBL:
AC026774,
AK094917,
AC113404,
BC100824,
BC100825,
BC100826,
AC108091,
BC100827,
KC877017,
AB028977,
AC026783
Ensembl:
ENSG00000122012
KO:
hsa:22987
|
| Nucleutide sequences |
EMBL-CDS:
AAI00828.1,
AAI00827.1,
BAA83006.1,
AAI00826.1,
AAI00825.1,
BAG52953.1
Ensembl_TRS:
ENST00000502798,
ENST00000322285
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000423541,
ENSP00000316983
RefSeq:
XP_011541584.2,
XP_016864733.1,
NP_055794.3,
XP_011541583.1,
NP_001284645.1
|
| Others |
UniRef100:
UniRef100_Q496J9,
UniRef100_B3KT41
UniRef90:
UniRef90_Q496J9,
UniRef90_F6PIT8
UniRef50:
UniRef50_Q496J9
UniGene:
Hs.663229
CCDS:
CCDS43331.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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