| Type | Description |
|---|---|
| Definition | centromere protein E |
| Date | Results | Publications |
|---|---|---|
| 2014-01-11 12:14:00 | Exacerbating chromosome missegregation in CENP-E+/- mice by reducing levels of another mitotic checkpoint component, Mad2, results in elevated cell death and decreased tumor formation compared with reduction of either protein alone. | 24133140 |
| 2012-07-21 11:07:00 | CENP-E stabilises BubR1, thereby impacting meiosis I progression, and mediates bi-orientation by promoting kinetochore reorientation and preventing chromosomal drift towards the poles. | 22513372 |
| 2010-01-21 00:00:00 | results suggest that CENP-E is implicated in the spindle checkpoint, and in chromosome alignment, during the two meiotic divisions in vertebrate males | 12068923 |
| 2010-01-21 00:00:00 | Shugoshin 2 is necessary for the loading of MCAK at the inner centromere, but is dispensable for the loading of the outer kinetochore proteins BubR1 and CENP-E. | 19283064 |
| 2010-01-21 00:00:00 | Deletion of the mouse gene CENP-E causes unstable kinetochore-microtubule capture and chromosomal instability. (CENP-E) | 12361599 |
| Type | IDs |
|---|---|
| Synonymous | 312kDa, AU019344, BC049989, C530022J18, CENP-E, Kif10 |
| Gene |
UniProtKB-ID:
CENPE_MOUSE,
E9QKK1_MOUSE
UniprotKB:
Q6RT24,
E9QKK1
UniParc:
UPI00004351F8,
UPI0000232015
EMBL:
BC052843,
AK049676,
BC049989,
BC059032,
AK133445,
AC104874,
BC106096,
AY493378,
AB001426
Ensembl:
ENSMUSG00000045328
KO:
mmu:229841
|
| Nucleutide sequences |
EMBL-CDS:
AAH52843.1,
BAE21661.1,
AAH49989.1,
AAH59032.1,
BAA22386.1,
AAI06097.1,
AAR85498.1,
BAC33868.1
Ensembl_TRS:
ENSMUST00000062893
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000057938
RefSeq:
NP_776123.3
|
| Others |
UniRef100:
UniRef100_Q6RT24,
UniRef100_E9QKK1
UniRef90:
UniRef90_Q6RT24
UniRef50:
UniRef50_Q02224
UniGene:
Mm.161470
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32325033 |
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Cell Syst Reza Pourhaghighi , Peter E A Ash , Sadhna Phanse , Florian Goebels , Lucas Z M Hu , Siwei Chen , Yingying Zhang , Shayne D Wierbowski , Samantha Boudeau , Mohamed T Moutaoufik , Ramy H Malty , Edyta Malolepsza , Kalliopi Tsafou , Aparna Nathan , Graham Cromar , Hongbo Guo , Ali Al Abdullatif , Daniel J Apicco , Lindsay A Becker , Aaron D Gitler , Stefan M Pulst , Ahmed Youssef , Ryan Hekman , Pierre C Havugimana , Carl A White , Benjamin C Blum , Antonia Ratti , Camron D Bryant , John Parkinson , Kasper Lage , Mohan Babu , Haiyuan Yu , Gary D Bader , Benjamin Wolozin , Andrew Emili |
2020-04-22 | - |
| 30713523 |
Front Endocrinol (Lausanne) Farzad Asadi , Savita Dhanvantari |
2018-01-01 | - |
| 28671696 |
Nat. Neurosci. Jing Li , Wangshu Zhang , Hui Yang , Daniel P Howrigan , Brent Wilkinson , Tade Souaiaia , Oleg V Evgrafov , Giulio Genovese , Veronica A Clementel , Jennifer C Tudor , Ted Abel , James A Knowles , Benjamin M Neale , Kai Wang , Fengzhu Sun , Marcelo P Coba |
2017-08-01 | - |
| 27626380 |
High-throughput discovery of novel developmental phenotypes. Nature Mary E Dickinson , Ann M Flenniken , Xiao Ji , Lydia Teboul , Michael D Wong , Jacqueline K White , Terrence F Meehan , Wolfgang J Weninger , Henrik Westerberg , Hibret Adissu , Candice N Baker , Lynette Bower , James M Brown , L Brianna Caddle , Francesco Chiani , Dave Clary , James Cleak , Mark J Daly , James M Denegre , Brendan Doe , Mary E Dolan , Sarah M Edie , Helmut Fuchs , Valerie Gailus-Durner , Antonella Galli , Alessia Gambadoro , Juan Gallegos , Shiying Guo , Neil R Horner , Chih-Wei Hsu , Sara J Johnson , Sowmya Kalaga , Lance C Keith , Louise Lanoue , Thomas N Lawson , Monkol Lek , Manuel Mark , Susan Marschall , Jeremy Mason , Melissa L McElwee , Susan Newbigging , Lauryl M J Nutter , Kevin A Peterson , Ramiro Ramirez-Solis , Douglas J Rowland , Edward Ryder , Kaitlin E Samocha , John R Seavitt , Mohammed Selloum , Zsombor Szoke-Kovacs , Masaru Tamura , Amanda G Trainor , Ilinca Tudose , Shigeharu Wakana , Jonathan Warren , Olivia Wendling , David B West , Leeyean Wong , Atsushi Yoshiki , International Mouse Phenotyping Consortium , Jackson Laboratory , Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris (ICS) , Charles River Laboratories , MRC Harwell , Toronto Centre for Phenogenomics , Wellcome Trust Sanger Institute , RIKEN BioResource Center , Daniel G MacArthur , Glauco P Tocchini-Valentini , Xiang Gao , Paul Flicek , Allan Bradley , William C Skarnes , Monica J Justice , Helen E Parkinson , Mark Moore , Sara Wells , Robert E Braun , Karen L Svenson , Martin Hrabe de Angelis , Yann Herault , Tim Mohun , Ann-Marie Mallon , R Mark Henkelman , Steve D M Brown , David J Adams , K C Kent Lloyd , Colin McKerlie , Arthur L Beaudet , Maja BuÄan , Stephen A Murray |
2016-09-22 | - |
| 26496610 |
A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell Marco Y Hein , Nina C Hubner , Ina Poser , Jürgen Cox , Nagarjuna Nagaraj , Yusuke Toyoda , Igor A Gak , Ina Weisswange , Jörg Mansfeld , Frank Buchholz , Anthony A Hyman , Matthias Mann |
2015-10-22 |
Cep85l,
Rcc1,
Zbtb48,
Bsdc1,
Kifc1,
Ccp110,
Ints4,
Slc6a8,
Cenpi,
Nup107,
Xpo1,
Fbxw11,
Tubg1,
Csnk1d,
Bap1,
Ptpn23,
Tecpr2,
Slain1,
Ankrd28,
Prkaa1,
Espl1,
Gbf1,
Cdc20,
Cenpf,
Trip11,
Mbd5,
Kif22,
Dut,
Srsf1,
Actb,
Spred2,
Akt2,
Mta1,
Tgs1,
Pip4k2c,
Ankfy1,
Apc,
Ar,
Rhoa,
Atp2a2,
Atp5a1,
Atp7a,
Cep131,
Bach1,
Bcl7c,
Bmpr1a,
Brca1,
Bub1,
Bub1b,
C1qbp,
Anxa2,
Calu,
Cbx1,
Cbx4,
Cct2,
Cct3,
Cct4,
Cct7,
Cct8,
Cd2ap,
Cdk1,
Cdc37,
Cdh1,
Chek1,
Cit,
Copa,
Crebbp,
Cry1,
Csk,
Smc3,
Dctn1,
Ddb1,
Cdk2ap1,
Mapre1,
Ect2,
Eef1a1,
Eif3a,
Mark2,
Evpl,
Ewsr1,
Wdr5,
Dclre1b,
Fbl,
Fgfr1,
Flot1,
Flot2,
B4galt1,
Gnb1,
Gspt1,
Hdac6,
Herc2,
Hsf1,
Hsph1,
Elavl1,
Id2,
Cyr61,
Cep250,
Insr,
Eif3e
|
| 26410627 |
Immunity John P Ray , Matthew M Staron , Justin A Shyer , Ping-Chih Ho , Heather D Marshall , Simon M Gray , Brian J Laidlaw , Koichi Araki , Rafi Ahmed , Susan M Kaech , Joe Craft |
2015-10-20 |
Akt1,
Il2,
Mtor
|
| 24194600 |
Nucleic Acids Res. Gautier Koscielny , Gagarine Yaikhom , Vivek Iyer , Terrence F Meehan , Hugh Morgan , Julian Atienza-Herrero , Andrew Blake , Chao-Kung Chen , Richard Easty , Armida Di Fenza , Tanja Fiegel , Mark Grifiths , Alan Horne , Natasha A Karp , Natalja Kurbatova , Jeremy C Mason , Peter Matthews , Darren J Oakley , Asfand Qazi , Jack Regnart , Ahmad Retha , Luis A Santos , Duncan J Sneddon , Jonathan Warren , Henrik Westerberg , Robert J Wilson , David G Melvin , Damian Smedley , Steve D M Brown , Paul Flicek , William C Skarnes , Ann-Marie Mallon , Helen Parkinson |
2014-01-01 | - |
| 24154525 |
Development Jeremy A Miller , Jason Nathanson , Daniel Franjic , Sungbo Shim , Rachel A Dalley , Sheila Shapouri , Kimberly A Smith , Susan M Sunkin , Amy Bernard , Jeffrey L Bennett , Chang-Kyu Lee , Michael J Hawrylycz , Allan R Jones , David G Amaral , Nenad Å estan , Fred H Gage , Ed S Lein |
2013-11-01 |
Rpp25,
Gldc,
Rhoq,
Psat1,
Tm6sf1,
Slc14a1,
Rimklb,
Nusap1,
Mybpc1,
Npy,
Bmp3,
Adgrv1,
Dlx1as,
Acadl,
Laptm4b,
Pawr,
Adra1a,
Alcam,
Aldoc,
Necab2,
Ank1,
Apoe,
Nr2f2,
Aqp4,
Rnd2,
Arnt2,
Bcan,
Bcat1,
Fabp7,
Zfp36l1,
C1qc,
Calb2,
Capn2,
Car2,
Cbln2,
Cbs,
Ccnd2,
Cd24a,
Entpd2,
Cd63,
Cd81,
Cd9,
Cdh11,
Cdh5,
Cit,
Ckb,
Cldn5,
Clu,
Cnp,
Cnr1,
Col19a1,
Col9a3,
Cort,
Cox6a2,
Cplx1,
Hapln1,
Cryab,
Csrp1,
Cst3,
Ctsd,
Ctsl,
Ctss,
Cux2,
Dbi,
Dcx,
Asap1,
Dio2,
Dlx1,
Cdk2ap1,
Ect2,
Egfr,
Eps8,
Erbb4,
Eya4,
Elmo1,
Fasn,
Fgf12,
Fgfr1,
Gaa,
Gabrg3,
Gad1,
Gad2,
Gap43,
Gfap,
Gpr83,
Gja1,
Gjd2,
Glul,
Glrb,
Gnai1,
Gnas,
Got1,
Adgrg1,
Cdca3,
Gria4,
Grik1,
Grpr,
Hbb-b1,
Hbb-b2
|
| 24133140 |
Chromosome missegregation rate predicts whether aneuploidy will promote or suppress tumors. Proc. Natl. Acad. Sci. U.S.A. Alain D Silk , Lauren M Zasadil , Andrew J Holland , Benjamin Vitre , Don W Cleveland , Beth A Weaver |
2013-10-29 |
Cenpe,
Mad2l1
|
| 23541922 |
Dev. Cell Liming Gui , Hayden Homer |
2013-04-15 |
Ccnb2,
Ndc80
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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