| Type | Description |
|---|---|
| Definition | PAX interacting protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-04-28 11:41:00 | PAXIP1 and 53BP1 protein levels followed gene expression results, i.e., are intrinsically correlated, and also reduced in more advanced breast cancer tumors. | 28475402 |
| 2017-07-01 12:00:00 | PAXIP1 is involved in sensitizing lung cancer cells to the WEE1 inhibitor AZD1775 in combination with platinum-based treatment. | 27196765 |
| 2015-07-04 16:16:00 | PTIP promotes double-strand break repair through a direct role in homologous recombination. | 20088963 |
| 2015-05-30 12:14:00 | PPM1B can dephosphorylate the Pax2 activation domain and displace the adaptor protein PTIP, thus inhibiting H3K4 methylation and gene activation. | 25631048 |
| 2015-02-14 11:25:00 | uncovered a nuclease, Artemis, as a PTIP-binding protein | 25512557 |
| Type | IDs |
|---|---|
| Synonymous | CAGF28, CAGF29, PACIP1, PAXIP1L, PTIP, TNRC2 |
| Gene |
UniProtKB-ID:
PAXI1_HUMAN
UniprotKB:
Q6ZW49
UniParc:
UPI00001C0919,
UPI0000141032,
UPI00004166F9
EMBL:
BC033781,
BX640616,
BC008328,
AK307417,
U80735,
AK123600,
AC093726,
BX538201,
AK123044
Ensembl:
ENSG00000157212
KO:
hsa:22976
|
| Nucleutide sequences |
EMBL-CDS:
AAH33781.1,
BAC85657.1,
AAP21865.1,
AAH08328.1,
AAB91434.1,
CAE45762.1,
CAD98066.1,
BAC85523.1
Gene_ORFName:
CAGF28
Ensembl_TRS:
ENST00000404141,
ENST00000397192
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000384048,
ENSP00000380376
RefSeq:
XP_024302461.1,
XP_011514284.1,
XP_005249596.1,
XP_016867370.1,
XP_024302462.1,
NP_031375.3,
XP_011514285.1
|
| Others |
UniRef100:
UniRef100_Q6ZW49
UniRef90:
UniRef90_Q6ZW49
UniRef50:
UniRef50_Q6ZW49
UniGene:
Hs.443881
CCDS:
CCDS47753.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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