| Type | Description |
|---|---|
| Definition | adenosine monophosphate deaminase 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-05-05 12:20:00 | AMPD1 is an adenosine monophosphate deaminase that catalyzes the deamination of AMP to IMP. An elevated AMP level and almost complete lack of IMP was detected in the skeletal muscle of E18.5 Ampd1(tm1a/tm1a) mice. | 27775065 |
| 2016-03-12 10:08:00 | AMPD1 deficiency activates AMPK/Akt/mTORC1/p70 S6 kinase axis in skeletal muscle after high fat diet challenge, but not in normal chow diet. These changes may contribute to improve insulin resistance. | 25887856 |
| 2015-07-04 13:43:00 | Disruption of the AMPD1 gene leads to a less severe state of insulin resistance, improved glucose tolerance and enhanced insulin clearance in mice fed a high-fat diet. Data suggest that AMPD may be a new drug target for reversing insulin resistance. | 25511531 |
| 2013-01-12 10:47:00 | AMPD1 deficiency is acquired prior to overt muscle inflammation and is responsible, at least in part, for the muscle weakness that occurs in the mouse model of myositis. | 22806328 |
| Type | IDs |
|---|---|
| Synonymous | AI553520, Ampd-1 |
| Gene |
UniProtKB-ID:
AMPD1_MOUSE
UniprotKB:
Q3V1D3
UniParc:
UPI000060475C
EMBL:
AK132524,
AC163297,
AC150894
Ensembl:
ENSMUSG00000070385
KO:
mmu:229665
|
| Nucleutide sequences |
EMBL-CDS:
BAE21218.1
Ensembl_TRS:
ENSMUST00000090715
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000088217
RefSeq:
NP_001028475.2,
XP_006501463.2
|
| Others |
UniRef100:
UniRef100_Q3V1D3
UniRef90:
UniRef90_Q3V1D3
UniRef50:
UniRef50_P23109
UniGene:
Mm.331272
CCDS:
CCDS38571.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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