| Type | Description |
|---|---|
| Definition | protein inhibitor of activated STAT 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:13:00 | Cancer exosome-derived miR-9 and miR-181a promote the development of early-stage MDSCs via interfering with SOCS3 and PIAS3 respectively in breast cancer. | 32398867 |
| 2020-04-04 10:27:00 | PIAS3 could have therapeutic benefits in patients with Spondyloarthritis. | 30630513 |
| 2019-07-13 10:41:00 | PIAS3-mediated feedback loops control cell proliferation and function as robust driving forces for Colitis-associated colorectal cancer (CAC) progression. | 29896300 |
| 2018-05-26 12:00:00 | Results show that PIAS3 levels are reduced in a mouse model of atherosclerotic lesions and that its expression decreases in conjunction with increases in interleukin-6 expression and disease severity. These findings provide evidence that results indicate that PIAS3 is a critical repressor of atherosclerosis progression. | 27845432 |
| 2015-06-27 10:16:00 | Data indicate that PIAS3 (protein inhibitor of activated interaction modulates EKLF (erythroid Kruppel-like factor) activity in a promoter-dependent and SUMO-independent manner. | 25713074 |
| Type | IDs |
|---|---|
| Synonymous | Pias3l |
| Gene |
UniProtKB-ID:
PIAS3_MOUSE
UniprotKB:
O54714
UniParc:
UPI0000190A1D,
UPI0000470ED4,
UPI000002876A
EMBL:
BC051252,
AK077551,
BC023128,
AK040619,
AF034080
Ensembl:
ENSMUSG00000028101
KO:
mmu:229615
|
| Nucleutide sequences |
EMBL-CDS:
AAH23128.1,
AAH51252.1,
AAB88902.3,
BAC30647.1,
BAC36858.1
Ensembl_TRS:
ENSMUST00000107076,
ENSMUST00000107077,
ENSMUST00000064900
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000069259,
ENSMUSP00000102691,
ENSMUSP00000102692
RefSeq:
NP_001159421.1,
NP_061282.2,
XP_006501456.1,
XP_036018966.1,
NP_666247.1,
XP_030108446.1
|
| Others |
UniRef100:
UniRef100_O54714
UniRef90:
UniRef90_O54714
UniRef50:
UniRef50_O54714
UniGene:
Mm.1635
CCDS:
CCDS51007.1,
CCDS17645.2,
CCDS38559.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员