| Type | Description |
|---|---|
| Definition | purinergic receptor P2X 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 13:58:00 | Progressive Dominant Hearing Loss (Autosomal Dominant Deafness-41) and P2RX2 Gene Mutations: A Phenotype-Genotype Study. | 31593348 |
| 2020-09-19 16:30:00 | Identification of a distinct desensitisation gate in the ATP-gated P2X2 receptor. | 31843194 |
| 2020-06-20 11:28:00 | A study of 3 hearing loss mutations in hP2X2 receptors that found while D273Y results in nonfunctional channels, V60L and G353R are conductive channels with diminished response to ATP, revealing the importance of full-strength activation of hP2X2 receptors in hearing protection. | 31636190 |
| 2018-09-22 11:02:00 | identified P2RX2, KCNQ5, ERBB3 and SOCS3 to be associated with the progression of age-related hearing impairment | 29325454 |
| 2018-05-26 11:48:00 | These findings indicate that the CaMKII-mediated GluA1 phosphorylation of S567 and S831 is critical for P2X2-mediated AMPAR internalization and ATP-driven synaptic depression. | 27624155 |
| Type | IDs |
|---|---|
| Synonymous | DFNA41, P2X2 |
| Gene |
UniProtKB-ID:
P2RX2_HUMAN,
Q32MC3_HUMAN
UniprotKB:
Q9UBL9,
Q32MC3
UniParc:
UPI000002B049,
UPI000002B04A,
UPI000002B04B,
UPI0000130FF3,
UPI000002B04C,
UPI00005DC750,
UPI000052A468,
UPI000002B048
EMBL:
AF190824,
AF260429,
AF190823,
AF109388,
AF190826,
AF190825,
AF260426,
AF260428,
AC131212,
AF109387,
BC109200,
AF260427,
AF190822,
AY346374
Ensembl:
ENSG00000187848
KO:
hsa:22953
|
| Nucleutide sequences |
EMBL-CDS:
AAF19174.1,
AAF19171.1,
AAF74201.1,
AAQ54329.1,
AAF19173.1,
AAF74203.1,
AAF74204.1,
AAF19172.1,
AAF74202.1,
AAF19170.1,
AAD42947.1,
AAD42948.1,
AAI09201.1
Ensembl_TRS:
ENST00000449132,
ENST00000351222,
ENST00000352418,
ENST00000643471,
ENST00000343948,
ENST00000350048,
ENST00000348800,
ENST00000542301
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000344502,
ENSP00000405531,
ENSP00000343339,
ENSP00000345095,
ENSP00000343904,
ENSP00000494644,
ENSP00000341419,
ENSP00000444477
RefSeq:
NP_057402.1,
NP_777361.1,
NP_036358.2,
XP_016874524.1,
XP_005266212.1,
XP_005266211.1,
XP_005266213.1,
NP_001269093.1,
NP_001269094.1,
NP_733783.1,
XP_011533088.1,
NP_733782.1,
NP_777362.1
|
| Others |
UniRef100:
UniRef100_Q9UBL9,
UniRef100_Q32MC3
UniRef90:
UniRef90_A0A2I3LHR1,
UniRef90_Q9UBL9
UniRef50:
UniRef50_P49653-2,
UniRef50_Q9UBL9
UniGene:
Hs.258580
CCDS:
CCDS31930.1,
CCDS31934.1,
CCDS31935.1,
CCDS31933.1,
CCDS31931.1,
CCDS61286.1,
CCDS31932.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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