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22948 CCT5

22948

CCT5

chaperonin containing TCP1 subunit 5

protein-coding

Homo sapiens

基因描述

Type Description
Definition chaperonin containing TCP1 subunit 5

研究结论

Date Results Publications
2021-02-27 13:48:00 A Novel CCT5 Missense Variant Associated with Early Onset Motor Neuropathy. 33076433
2015-10-03 10:55:00 CCT5 complex caps mutant mHTT fibrils at their tips and encapsulates mHTT oligomers, providing a structural description of the inhibition of mHTTQ46-Ex1 by CCT5 complex and a shared mechanism of mHTT inhibition between TRiC chaperonin and the CCT5 complex 25995452
2014-12-20 13:19:00 H147R CCT5 was not as efficient in chaperoning these substrates as wild type CCT5. 25124038
2013-08-31 12:04:00 Both CCT4 and CCT5 homo-oligomers have the property of forming 8-fold double rings absent the other subunits, and these complexes carry out chaperonin reactions without other partner subunits. 23612981
2012-05-19 10:23:00 introduction of the truncated human CCT epsilon subunit into yeast cells 22232265

名称对应

Type IDs
Synonymous CCT-epsilon, CCTE, HEL-S-69, PNAS-102, TCP-1-epsilon
Gene
UniProtKB-ID: TCPE_HUMAN, B4DYC8_HUMAN, E7ENZ3_HUMAN, B7ZAR1_HUMAN, B4DX08_HUMAN, V9HW37_HUMAN, E9PCA1_HUMAN, B4DDU6_HUMAN
UniprotKB: P48643, B4DYC8, E7ENZ3, B7ZAR1, B4DX08, V9HW37, E9PCA1, B4DDU6
UniParc: UPI00017A8205, UPI0001915437, UPI00017A823A, UPI00017A6BD8, UPI0000D9B3AA, UPI0000001C34, UPI0001D3B13A, UPI00017A8284
EMBL: AK302383, CH471102, AK289353, AC012640, BC006543, AK316376, BC035499, AK302368, AK293341, FJ224303, D43950, AK290393, AK301760
Ensembl: ENSG00000150753
KO: hsa:22948
Nucleutide sequences
EMBL-CDS: BAF83082.1, BAG63700.1, BAA07894.2, AAH35499.1, EAX08072.1, BAF82042.1, AAH06543.1, BAG63690.1, BAH14747.1, BAG63220.1, ACI45995.1, BAG56857.1
Ensembl_TRS: ENST00000280326, ENST00000506600, ENST00000515390, ENST00000515676, ENST00000503026
Protein sequencees
Ensembl_PRO: ENSP00000423052, ENSP00000280326, ENSP00000426923, ENSP00000427297, ENSP00000423318
RefSeq: NP_001293084.1, NP_036205.1, NP_001293085.1, NP_001293082.1, NP_001293083.1
Others
UniRef100: UniRef100_P48643, UniRef100_B4DYC8, UniRef100_E9PCA1, UniRef100_B4DDU6, UniRef100_B4DX08, UniRef100_E7ENZ3
UniRef90: UniRef90_P48643, UniRef90_P80316
UniRef50: UniRef50_P80316, UniRef50_P48643
UniGene: Hs.1600
CCDS: CCDS82990.1, CCDS3877.1

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