| Type | Description |
|---|---|
| Definition | double homeobox 4 like 1 (pseudogene) |
| Date | Results | Publications |
|---|---|---|
| 2014-07-12 10:06:00 | these data support a model in which DME1 and DME2 myogenic enhancers associate with the DUX4 promoter in skeletal myocytes and activate transcription when epigenetically derepressed in FSHD, resulting in the pathological misexpression of DUX4-fl. | 24636994 |
| 2014-06-21 11:01:00 | proposed that Wnt/beta-catenin signaling is important for transcriptional repression of DUX4 | 23821646 |
| 2014-06-14 11:59:00 | Impact of Dux4 on p53/p21 signal pathway, which controls the checkpoint in cell cycle progression. Overexpression of Dux4 increased p21 mRNA and protein level, while expression of p53, phospho-p53 remained unchanged. | 24589735 |
| 2014-06-14 10:58:00 | DUX4 possesses redundant mechanisms to assure nuclear entrance and that its various transcription-factor associated domains play an essential role in cell toxicity. | 24116060 |
| 2014-05-17 10:15:00 | Our findings demonstrate a role for DUX4 and repetitive elements in mammalian germline evolution and in FSHD muscular dystrophy. | 24278031 |
| Type | IDs |
|---|---|
| Synonymous | DUX10, DUX4 |