| Type | Description |
|---|---|
| Definition | SH3 and multiple ankyrin repeat domains 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:29:00 | Arginine methylation of SHANK2 by PRMT7 promotes human breast cancer metastasis through activating endosomal FAK signalling. | 32844749 |
| 2019-10-05 12:56:00 | Study provides evidence that a direct regulatory link exists between miR-137 and SHANK2 and supports the finding that miR-137 signaling might be altered in schizophrenia. | 29665782 |
| 2019-06-22 10:38:00 | Our results indicate SHANK2 is a susceptibility gene for Autism spectrum disorder (ASD) in Chinese children | 29934968 |
| 2019-05-25 10:12:00 | Findings provide evidence for hyperconnectivity and altered transcriptome in SHANK2 neurons derived from autism spectrum disorder subjects. | 30911184 |
| 2017-12-02 12:26:00 | We report a deletion including the SHANK2 gene in a female child with dysmorphic features, microcephaly, and global developmental delay, providing additional evidence for SHANK2 involvement in intellectual disability | 28211979 |
| Type | IDs |
|---|---|
| Synonymous | AUTS17, CORTBP1, CTTNBP1, ProSAP1, SHANK, SPANK-3 |
| Gene |
UniProtKB-ID:
SHAN2_HUMAN,
A6NHU9_HUMAN,
C0SPH0_HUMAN,
A0A590UJ45_HUMAN
UniprotKB:
Q9UPX8,
A6NHU9,
C0SPH0,
A0A590UJ45
UniParc:
UPI000198F7E3,
UPI0007DC5D6B,
UPI000013E13A,
UPI00001617F1,
UPI0001B09234,
UPI000198F7E4,
UPI000198F7E5
EMBL:
AB208026,
AP004370,
AP000590,
AP003783,
DQ152234,
AP005401,
AB028945,
AP001271,
KF455409,
AC234421,
AB208025,
AP001648,
BC093885,
AP003967,
BC112097,
AB208027,
AF141901
Ensembl:
ENSG00000162105
KO:
hsa:22941
|
| Nucleutide sequences |
EMBL-CDS:
BAH37016.1,
AAF02496.1,
AAH93885.1,
BAH37017.1,
BAA82974.1,
AAZ77790.1,
AAI12098.1,
BAH37018.1
Ensembl_TRS:
ENST00000656230,
ENST00000601538,
ENST00000338508,
ENST00000659264
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000469689,
ENSP00000499561,
ENSP00000345193,
ENSP00000499270
RefSeq:
XP_016872877.1,
XP_016872879.1,
XP_016872876.1,
NP_036441.2,
NP_573573.2,
NP_001366155.1,
XP_016872878.1
|
| Others |
UniRef100:
UniRef100_A6NHU9,
UniRef100_A0A590UJ45,
UniRef100_Q9UPX8
UniRef90:
UniRef90_A0A0D9RAI8,
UniRef90_A6NHU9,
UniRef90_Q9UPX8
UniRef50:
UniRef50_Q80Z38-2
UniGene:
Hs.268726
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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