| Type | Description |
|---|---|
| Definition | ribose 5-phosphate isomerase A |
| Date | Results | Publications |
|---|---|---|
| 2019-12-14 11:25:00 | We report on a subject with RPIA associated progressive leukoencephalopathy with elevated urine arabitol and ribitol levels and a novel missense variant c.770T>C p.(Ile257Thr) in exon 8 of RPIA. We also compare the phenotypes of all the four subjects. Our report confirms the phenotype and the genetic cause of this condition. | 31247379 |
| 2019-10-26 11:14:00 | SRC-2 controls the pentose phosphate pathway through RPIA in human endometrial cancer cells. | 30177747 |
| 2017-12-02 10:59:00 | The results are consistent with a model in which RPIA suppresses autophagy and LC3 processing by modulation of redox signaling. | 27328773 |
| 2016-04-09 10:23:00 | CRC cells that overexpressed miR124 or with knockdown of RPIA or PRPS1 had reduced DNA synthesis and proliferation, whereas cells incubated with an inhibitor of miR124 had significantly increased DNA synthesis and proliferation and formed more colonies. | 26248089 |
| 2016-03-08 18:23:00 | In this work, through an in silico comparative analysis between the genomes of Leishmania major and Homo sapiens, the enzyme ribose 5-phosphate isomerase (R5PI) was indicated as a promising molecular target. | 25528729 |
| Type | IDs |
|---|---|
| Synonymous | RPI, RPIAD |
| Gene |
UniProtKB-ID:
RPIA_HUMAN
UniprotKB:
P49247
UniParc:
UPI0000037A98
EMBL:
AY050633,
L35035,
BC015529
Ensembl:
ENSG00000153574
KO:
hsa:22934
|
| Nucleutide sequences |
EMBL-CDS:
AAK95569.1,
AAH15529.2
Ensembl_TRS:
ENST00000283646
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000283646
RefSeq:
NP_653164.2
|
| Others |
UniRef100:
UniRef100_P49247
UniRef90:
UniRef90_P49247
UniRef50:
UniRef50_P49247
UniGene:
Hs.469264
CCDS:
CCDS2004.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员