| Type | Description |
|---|---|
| Definition | selenophosphate synthetase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-25 12:37:00 | SEPHS1 expression is high in undifferentiated embryonic stem cells.SEPHS1 expression is required to obtain pluripotency.SEPHS1 plays a role in the embryonic stem cell survival via reactive oxygen species signaling and apoptosis. | 31607477 |
| 2017-06-24 11:26:00 | Data confirm interactions among components of the early steps of the selenocysteine biosynthesis pathway (SEPSECS, SECP43, SEPHS1, and SEPHS2); SECP43, which interacts with SEPSECS and SEPHS1, is a globular protein that forms oligomers in vivo. | 28414460 |
| 2013-03-30 12:17:00 | Three SNPs in SEPSECS and SEPHS1 were found to significantly interact with serum selenium level and Crohn's Disease. | 23112913 |
| 2010-08-09 12:12:00 | Five alternative splice variants of human SPS1 (major type, DeltaE2, DeltaE8, +E9, +E9a) were identified wherein +E9 and +E9a make the same protein. | 20471958 |
| 2010-01-21 00:00:00 | the Sps1-encoded enzyme depends on a selenium salvage system that recycles l-selenocysteine, whereas the Sps2 enzyme can function with a selenite assimilation system | 15534230 |
| Type | IDs |
|---|---|
| Synonymous | SELD, SPS, SPS1 |
| Gene |
UniProtKB-ID:
SPS1_HUMAN
UniprotKB:
P49903
UniParc:
UPI0000E222F8,
UPI0000D4D572,
UPI000046FD61,
UPI0000135E82
EMBL:
CH471072,
AL355870,
AL138764,
GU954546,
GU954548,
BC063816,
U34044,
GU954549,
GU954545,
BC000941,
AK301568,
GU954547
Ensembl:
ENSG00000086475
KO:
hsa:22929
|
| Nucleutide sequences |
EMBL-CDS:
ADF78124.1,
ADF78123.1,
EAW86292.1,
BAG63062.1,
EAW86290.1,
AAH63816.1,
EAW86289.1,
ADF78121.1,
EAW86291.1,
ADF78120.1,
ADF78122.1,
EAW86293.1,
AAA87567.1,
AAH00941.1
Ensembl_TRS:
ENST00000327347,
ENST00000378614,
ENST00000545675
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000367893,
ENSP00000441119,
ENSP00000367877
RefSeq:
XP_016871432.1,
NP_001182531.1,
NP_001182533.1,
NP_036379.2,
NP_001362698.1
|
| Others |
UniRef100:
UniRef100_P49903
UniRef90:
UniRef90_P49903
UniRef50:
UniRef50_P49903
UniGene:
Hs.124027
CCDS:
CCDS55702.1,
CCDS7098.1,
CCDS55703.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员