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22908 SACM1L

22908

SACM1L

SAC1 like phosphatidylinositide phosphatase

protein-coding

Homo sapiens

基因描述

Type Description
Definition SAC1 like phosphatidylinositide phosphatase

研究结论

Date Results Publications
2020-02-29 12:15:00 The activity of Sac1 across ER-TGN contact sites requires the four-phosphate-adaptor-protein-1. 30659099
2018-04-21 10:05:00 the component proteins of the machinery, OSBP, VAP, SAC1, and PITPNB, are all essential host factors for AiV replication. Importantly, the machinery is directly recruited to the RNA replication sites through previously unknown interactions of VAP/OSBP/SAC1 with the AiV proteins and with ACBD3. 29367253
2018-04-07 11:47:00 results demonstrate that Sac1 expression in either the ER or Golgi apparatus has a minimal impact on the PI-4P that regulates OSBP activity or recruitment to contact sites 28471037
2015-11-14 10:15:00 data suggest a model in which the 14-3-3 protein mediates SAC1 traffic from the ER through direct interaction with a sorting signal and COPII 26056309
2010-01-21 00:00:00 the enzymatic function of hSAC1 provides a switch for accessibility of the COPI interaction motif 14527956

名称对应

Type IDs
Synonymous SAC1
Gene
UniProtKB-ID: SAC1_HUMAN, E9PGZ4_HUMAN, B4DVV3_HUMAN
UniprotKB: Q9NTJ5, E9PGZ4, B4DVV3
UniParc: UPI000198CAE4, UPI00017A7DCE, UPI000006EAA5, UPI00017A7559
EMBL: AJ289880, AJ297357, BC016559, AK296421, AK291142, AB020658, AC098476, AK301248, AL136831
Ensembl: ENSG00000211456
KO: hsa:22908
Nucleutide sequences
EMBL-CDS: AAH16559.1, CAB66765.1, CAB96871.1, BAA74874.2, CAB95945.1, BAG59083.1, BAF83831.1, BAG62815.1
Ensembl_TRS: ENST00000389061, ENST00000672477, ENST00000418611
Protein sequencees
Ensembl_PRO: ENSP00000373713, ENSP00000500361, ENSP00000396387
RefSeq: NP_001306001.1, NP_054735.3, NP_001306002.1, XP_011531802.1, NP_001306000.1
Others
UniRef100: UniRef100_B4DVV3, UniRef100_Q9NTJ5
UniRef90: UniRef90_Q9NTJ5, UniRef90_A0A452TGN4
UniRef50: UniRef50_H0Z3T9, UniRef50_Q9NTJ5
UniGene: Hs.156509
CCDS: CCDS33745.1

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