| Type | Description |
|---|---|
| Definition | aldolase, fructose-bisphosphate B |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 12:29:00 | downregulation of aldolase B and accumulation of fructose 1,6-bisphosphate promote clear cell renal cell carcinoma growth by counteracting oxidative stress | 30760861 |
| 2020-03-28 12:02:00 | high ALDOB expression impairs DNA mismatch repair and induces apoptosis in colon adenocarcinoma | 31564566 |
| 2019-09-21 11:04:00 | ALDOB knockdown or dietary fructose restriction suppresses growth of colorectal cancer (CRC) liver metastases, but not primary tumors or lung metastases, highlighting the importance of tumor microenvironment. | 29706565 |
| 2019-09-14 12:34:00 | Differential gene expression between islets from normoglycemic and hyperglycemic patients was prominent for the glycolytic enzyme ALDOB, mRNA level of ALDOB correlated negatively with insulin secretion and positively with HbA1c. The minor allele of the ALDOB variant rs550915 associated with significantly higher levels of C-peptide and insulin during oral glucose tolerance test and hyperglycemic clamp, respectively. | 30202879 |
| 2017-07-15 11:03:00 | Silencing Aldolase B activated epithelial markers and repressed mesenchymal markers, indicating inactivation of Aldolase B may lead to inhibition of epithelial-mesenchymal transition | 28558381 |
| Type | IDs |
|---|---|
| Synonymous | ALDB, ALDO2 |
| Gene |
UniProtKB-ID:
ALDOB_HUMAN,
A0A024R145_HUMAN
UniprotKB:
P05062,
A0A024R145
UniParc:
UPI000016A4A9
EMBL:
M15656,
X00270,
D00183,
X02747,
X01098,
AL353621,
M15657,
CH471105
Ensembl:
ENSG00000136872
KO:
hsa:229
|
| Nucleutide sequences |
EMBL-CDS:
BAA00125.1,
AAA51691.1,
CAA25072.1,
CAA25572.1,
EAW58951.1,
CAA26526.1,
EAW58952.1
Gene_ORFName:
hCG_27655
Ensembl_TRS:
ENST00000648758,
ENST00000648064,
ENST00000647789
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000497767,
ENSP00000497731,
ENSP00000497990
RefSeq:
NP_000026.2
|
| Others |
UniRef100:
UniRef100_P05062
UniRef90:
UniRef90_P05062
UniRef50:
UniRef50_P05062
UniGene:
Hs.530274
CCDS:
CCDS6756.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员