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22899 ARHGEF15

22899

ARHGEF15

Rho guanine nucleotide exchange factor 15

protein-coding

Homo sapiens

基因描述

Type Description
Definition Rho guanine nucleotide exchange factor 15

研究结论

Date Results Publications
2017-09-16 12:23:00 pathological elevation of Ephexin5 expression critically drives Abeta-induced memory impairment 28346227
2017-06-24 11:15:00 upregulation of ARHGEF15 contributes to the development of aggressive PDAC by increasing the growth and motility of the pancreatic cancer cells, thereby worsening the prognosis of these patients. 27145964
2013-03-02 13:12:00 Arhgef15 acts as an endothelial cell-specific GEF to mediate VEGF-induced Cdc42 activation and potentiate RhoJ inactivation, thereby promoting actin polymerization and cell motility. 23029280
2010-01-20 21:35:00 Observational study of gene-disease association. (HuGE Navigator) 19911011
2004-03-03 09:34:00 This paper presents functional studies determined in rat, mouse, and human tissues and cell lines. 12775584

名称对应

Type IDs
Synonymous ARGEF15, E5, Ephexin5, Vsm-RhoGEF
Gene
UniProtKB-ID: ARHGF_HUMAN, A0A0S2Z547_HUMAN
UniprotKB: O94989, A0A0S2Z547
UniParc: UPI000013D2C0
EMBL: AC135178, AB020722, BC036749, AK291626, KU178557, CH471108
Ensembl: ENSG00000198844
KO: hsa:22899
Nucleutide sequences
EMBL-CDS: EAW90060.1, BAF84315.1, BAA74938.2, AAH36749.1, ALQ34015.1
Ensembl_TRS: ENST00000361926, ENST00000421050
Protein sequencees
Ensembl_PRO: ENSP00000412505, ENSP00000355026
RefSeq: XP_011522039.1, XP_011522036.1, NP_776089.2, NP_079290.1, XP_011522037.1, XP_011522038.1
Others
UniRef100: UniRef100_O94989
UniRef90: UniRef90_O94989
UniRef50: UniRef50_Q5FWH6
UniGene: Hs.443109
CCDS: CCDS11139.1

全选

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