| Type | Description |
|---|---|
| Definition | DENN domain containing 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-01-19 10:49:00 | show that DENND3 binds actin through a surface of positively charged residues on the PHenn domain of Ran12 | 29352104 |
| 2017-07-15 10:17:00 | DENND3 is the exchange factor for the small GTPase Rab12 regulated through an intramolecular interaction | 28249939 |
| 2016-03-12 10:05:00 | a novel signaling pathway identified whereby starvation-induced activation of ULK leads to phosphorylation of endogenous DENND3, with subsequent activation of Rab12 and initiation of membrane trafficking events required for autophagy | 25925668 |
| 2010-06-30 22:05:00 | Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | 20379614 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
DEND3_HUMAN
UniprotKB:
A2RUS2
UniParc:
UPI000035E813,
UPI000006EAD9,
UPI0000F095D1,
UPI00003CEFBA
EMBL:
AC040970,
AK131505,
BC133023,
BC144226,
AB020677,
AK058001
Ensembl:
ENSG00000105339
KO:
hsa:22898
|
| Nucleutide sequences |
EMBL-CDS:
AAI44227.1,
BAA74893.2,
BAB71630.1,
AAI33024.1,
BAD18649.1
Ensembl_TRS:
ENST00000262585,
ENST00000424248
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000262585,
ENSP00000410594
RefSeq:
XP_011515239.2,
NP_001339820.2,
NP_001339819.2,
NP_001349727.1,
XP_005250897.3,
XP_016868731.1,
XP_011515242.1,
XP_011515236.2,
XP_005250898.3,
XP_011515243.2,
XP_011515240.1,
XP_011515235.2,
XP_005250899.1,
NP_055772.3,
XP_016868730.1,
XP_016868732.1,
XP_011515241.1
|
| Others |
UniRef100:
UniRef100_A2RUS2
UniRef90:
UniRef90_A2RUS2
UniRef50:
UniRef50_A2RT67
UniGene:
Hs.18166
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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