| Type | Description |
|---|---|
| Definition | MLX interacting protein |
| Date | Results | Publications |
|---|---|---|
| 2020-12-26 13:11:00 | TXNIP induced by MondoA, rather than ChREBP, suppresses cervical cancer cell proliferation, migration and invasion. | 31782782 |
| 2020-09-26 13:05:00 | MondoA drives muscle lipid accumulation and insulin resistance. | 31287806 |
| 2020-03-28 10:04:00 | In response to acidosis, MondoA shows preferential binding to just two targets, TXNIP and its paralog ARRDC4. Because these transcriptional targets are suppressors of glucose uptake, the authors propose that MondoA is critical for restoring metabolic homeostasis in response to high energy charge. | 30717828 |
| 2018-05-26 11:31:00 | Data (including data from studies in knockout mice) suggest that MONDOA shuttles to nucleus of pancreatic beta-cells where it is required for induction of glucose-responsive genes arrestin domain-containing protein 4 (ARRDC4) and thioredoxin interacting protein (TXNIP). | 29282201 |
| 2017-09-30 10:08:00 | MondoA-directed programs have a key role in the coordinated control of myocyte lipid balance and insulin signaling | 27500491 |
| Type | IDs |
|---|---|
| Synonymous | MIR, MONDOA, bHLHe36 |
| Gene |
UniProtKB-ID:
MLXIP_HUMAN
UniprotKB:
Q9HAP2
UniParc:
UPI0000E59A38,
UPI0001596A21,
UPI0000D6226F,
UPI000006E5D1,
UPI000006F425
EMBL:
BC028309,
BC151841,
AF245481,
AF312918,
AF245480,
BC017656,
AB020674,
BC039704
Ensembl:
ENSG00000175727,
ENSG00000281178
KO:
hsa:22877
|
| Nucleutide sequences |
EMBL-CDS:
AAL55690.1,
AAI51842.1,
AAH39704.1,
AAL55689.1,
AAH28309.1,
AAG34121.1,
AAH17656.1,
BAA74890.2
Ensembl_TRS:
ENST00000538698,
ENST00000625732,
ENST00000629738,
ENST00000319080,
ENST00000377037
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000486569,
ENSP00000440769,
ENSP00000312834,
ENSP00000366236,
ENSP00000487003
RefSeq:
XP_006719356.1,
NP_055753.3,
XP_006719353.1,
XP_006719354.1,
XP_006719355.1,
XP_006719357.1
|
| Others |
UniRef100:
UniRef100_Q9HAP2
UniRef90:
UniRef90_Q9HAP2
UniRef50:
UniRef50_Q9HAP2
UniGene:
Hs.721711,
Hs.731847
CCDS:
CCDS73540.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员