| Type | Description |
|---|---|
| Definition | ectonucleotide pyrophosphatase/phosphodiesterase 4 |
| Date | Results | Publications |
|---|---|---|
| 2014-04-12 11:27:00 | The combined studies expand our understanding of NPP1 and NPP4 substrate specificity and range and provide a rational mechanism by which polymorphisms in NPP1 confer stroke resistance. | 24338010 |
| 2013-02-02 11:27:00 | NPP4 promotes hemostasis in vivo by augmenting ADP-mediated platelet aggregation at the site of vascular injury. | 22995898 |
| Type | IDs |
|---|---|
| Synonymous | NPP4 |
| Gene |
UniProtKB-ID:
ENPP4_HUMAN
UniprotKB:
Q9Y6X5
UniParc:
UPI0000048E43
EMBL:
AB020686,
AK291276,
AL035701,
BC018054
Ensembl:
ENSG00000001561
KO:
hsa:22875
|
| Nucleutide sequences |
EMBL-CDS:
BAA74902.2,
AAH18054.1,
BAF83965.1
Ensembl_TRS:
ENST00000321037
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000318066
RefSeq:
NP_055751.1
|
| Others |
UniRef100:
UniRef100_Q9Y6X5
UniRef90:
UniRef90_Q9Y6X5
UniRef50:
UniRef50_Q9Y6X5
UniGene:
Hs.643497
CCDS:
CCDS34468.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 26186194 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi |
2015-07-16 | - |
| 24338010 |
J Biol Chem Ronald A Albright , Deborah L Ornstein , Wenxiang Cao , William C Chang , Donna Robert , Martin Tehan , Denton Hoyer , Lynn Liu , Paul Stabach , Guangxiao Yang , Enrique M De La Cruz , Demetrios T Braddock |
2014-02-07 | - |
| 22995898 |
NPP4 is a procoagulant enzyme on the surface of vascular endothelium. Blood Ronald A Albright , William C Chang , Donna Robert , Deborah L Ornstein , Wenxiang Cao , Lynn Liu , Meredith E Redick , J Isaac Young , Enrique M De La Cruz , Demetrios T Braddock |
2012-11-22 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 19946888 |
Defining the membrane proteome of NK cells. J Mass Spectrom Dhimankrishna Ghosh , Dustin Lippert , Oleg Krokhin , John P Cortens , John A Wilkins |
2010-01-01 |
MED6,
PDCD6IP,
MED16,
PIGK,
DNAJB6,
FARSB,
DNM1L,
ABCF2,
HUWE1,
ARPC3,
ACTR3,
ACTR2,
RAD50,
PREB,
ACTR1B,
LRPPRC,
TRAP1,
BCAP31,
PLXNC1,
LPCAT3,
TNK2,
PSME3,
MPHOSPH9,
FLOT1,
DDX39A,
AK6,
ADAM10,
PLIN3,
CALCOCO2,
CDK9,
ABCC4,
ZMPSTE24,
AKAP8,
BET1,
MARCH6,
KATNB1,
ADAR,
EMC8,
BTN3A3,
ATP8A1,
NDC80,
CDIPT,
PGRMC2,
TUBGCP3,
ECI2,
COG5,
SLC25A17,
LRRC41,
SYNCRIP,
MYBBP1A,
DDX17,
CHERP,
HYOU1,
IPO7,
NOP56,
ARL6IP5,
HTATIP2,
AGPAT1,
ARFGEF2,
RABAC1,
SLU7,
PRPF8,
PAICS,
CENPE,
PMVK,
KHDRBS1,
CELF1,
GNA13,
CFL1,
MGEA5,
YME1L1,
STAG2,
CTSC,
GIPC1,
HBS1L,
TUBGCP2,
PGRMC1,
MAN1A2,
PNPLA6,
MAGED2,
ADCY3,
EHD1,
TOMM34,
ERP29,
YWHAQ,
ASCC3,
GCN1,
IMMT,
ILVBL,
SLC27A4,
SLC27A3,
KIF2C,
GLIPR1,
CPSF6,
DDX52,
WWP2,
CNTRL,
CHD4,
KRR1
|
| 19490893 |
A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene. Cell Ji Luo , Michael J Emanuele , Danan Li , Chad J Creighton , Michael R Schlabach , Thomas F Westbrook , Kwok-Kin Wong , Stephen J Elledge |
2009-05-29 | - |
| 19056867 |
Large-scale proteomics and phosphoproteomics of urinary exosomes. J. Am. Soc. Nephrol. Patricia A Gonzales , Trairak Pisitkun , Jason D Hoffert , Dmitry Tchapyjnikov , Robert A Star , Robert Kleta , Nam Sun Wang , Mark A Knepper |
2009-02-01 | - |
| 16344560 |
Genome Res. Kouichi Kimura , Ai Wakamatsu , Yutaka Suzuki , Toshio Ota , Tetsuo Nishikawa , Riu Yamashita , Jun-ichi Yamamoto , Mitsuo Sekine , Katsuki Tsuritani , Hiroyuki Wakaguri , Shizuko Ishii , Tomoyasu Sugiyama , Kaoru Saito , Yuko Isono , Ryotaro Irie , Norihiro Kushida , Takahiro Yoneyama , Rie Otsuka , Katsuhiro Kanda , Takahide Yokoi , Hiroshi Kondo , Masako Wagatsuma , Katsuji Murakawa , Shinichi Ishida , Tadashi Ishibashi , Asako Takahashi-Fujii , Tomoo Tanase , Keiichi Nagai , Hisashi Kikuchi , Kenta Nakai , Takao Isogai , Sumio Sugano |
2006-01-01 |
Nefm,
MED6,
CDH2,
PDZK1P1,
DDTL,
ABI1,
GNPDA1,
GTF2IP4,
ZSCAN30,
SRA1,
TMEM170B,
HOTAIR,
FAM86JP,
LOC100126784,
C8orf88,
LOC100128006,
RAB28P5,
MYHAS,
CDC42P3,
LOC100128979,
LOC100128993,
KTN1-AS1,
LOC100129083,
LOC100129204,
TOPORS-AS1,
LINC00484,
ZNF37BP,
FAM47E,
MRVI1-AS1,
ZNF737,
LOC100130075,
MAPT-IT1,
MIR124-2HG,
LINC00861,
LOC100130238,
LOC100130357,
PARD6G-AS1,
LOC100130547,
NFYC-AS1,
EFCAB10,
LOC100130798,
SBK3,
LOC100130849,
LOC100130872,
LOC100130880,
LOC100130987,
LOC100131047,
LINC01135,
CKMT2-AS1,
ZBTB20-AS1,
WDR86-AS1,
CCDC183-AS1,
SNAP25-AS1,
NEMP2,
ZNF503-AS2,
MIR181A1HG,
DBIL5P,
HDAC6,
MZF1-AS1,
ARMCX4,
LINC00271,
ZNF717,
LOC100132057,
LOC100132111,
CALML3-AS1,
NDUFA6-AS1,
FRG1HP,
FCGR1CP,
GXYLT1P3,
GOLGA8F,
DCAF13P3,
IPO5P1,
MSC-AS1,
SMIM9,
FAM66A,
CD24,
UXT-AS1,
JHDM1D-AS1,
UBE2Q2P2,
TEN1,
JMJD7,
PLA2G4B,
LINC00930,
PDCD6IP,
HECTD2-AS1,
ZFHX4-AS1,
FAR2P2,
LOC100233156,
PCED1B-AS1,
PIGK,
LOC100270746,
LOC100270804,
LINC00940,
ERVV-2,
MEF2B,
ZNRF2P2,
NFE2L3P2,
LINC00894,
BCDIN3D-AS1
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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