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228550 Itpka

228550

Itpka

inositol 1,4,5-trisphosphate 3-kinase A

protein-coding

Mus musculus

基因描述

Type Description
Definition inositol 1,4,5-trisphosphate 3-kinase A

研究结论

Date Results Publications
2018-07-14 11:48:00 Thisstudy shows that overexpressed IP3-kinase A plays a role in some forms of hippocampus-dependent learning and memory tasks as well as in synaptic transmission and plasticity by regulating both presynaptic and postsynaptic functions. 29617377
2017-01-28 10:17:00 Findings demonstrate that IP3K-A plays an important role in regulating affective states by modulating metabotropic receptor signaling pathways and neural activity in the amygdala. 27053114
2012-05-12 11:11:00 At synapses of Inositol-1,4,5-trisphosphate 3-kinase-A deficient neurons the levels of Ins(1,4,5)P3-5-phosphatase (inpp5a) and sarcoplasmic/endoplasmic reticulum calcium ATPase pump-2b (serca2b) were increased. 22120525
2010-03-15 11:56:00 Inositol 1,4,5-trisphosphate 3-kinase-A is a new cell motility-promoting protein that increases the metastatic potential of tumor cells by two functional activities. 20022963
2010-01-21 00:00:00 These data show that the absence of expression of the three isoenzymes of Itpk does not prevent the formation of IP5 and IP6, at least in mouse embryonic fibroblasts.[Itpka, Itpkb, Itpkc] 17355905

名称对应

Type IDs
Gene
UniProtKB-ID: IP3KA_MOUSE
UniprotKB: Q8R071
UniParc: UPI0000027B53
EMBL: BC027291, AL844536
Ensembl: ENSMUSG00000027296
KO: mmu:228550
Nucleutide sequences
EMBL-CDS: AAH27291.1
Ensembl_TRS: ENSMUST00000028758
Protein sequencees
Ensembl_PRO: ENSMUSP00000028758
RefSeq: NP_666237.1
Others
UniRef100: UniRef100_Q8R071
UniRef90: UniRef90_P17105
UniRef50: UniRef50_P17105
UniGene: Mm.65337
CCDS: CCDS16607.1

全选

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研究热度

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