| Type | Description |
|---|---|
| Definition | AP2 associated kinase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-03 12:55:00 | The Serine/Threonine Kinase AP2-Associated Kinase 1 Plays an Important Role in Rabies Virus Entry. | 31905947 |
| 2020-03-21 11:22:00 | Author show that AAK1 promotes clearance of LRP6 from the plasma membrane to suppress the WNT pathway. | 30605688 |
| 2016-12-17 10:24:00 | Results present the first structures of AAK1 and BIKE which reveal that all members of the Numb-associated kinase family share unusual activation segment architecture. | 26853940 |
| 2016-01-02 11:00:00 | Two of these kinases that were classified as resistors were PX domain-containing serine/threonine kinase (PXK) and AP2-associated kinase 1 (AAK1), which promote receptor endocytosis and may enable cells to resist TRAIL-induced apoptosis | 25852190 |
| 2015-05-30 12:36:00 | AAK1 and GAK are critical regulators of HCV entry that function in part by activating EGFR, AP2M1, and NUMB, and as the molecular targets underlying the antiviral effect of sunitinib and erlotinib, respectively. | 25653444 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
AAK1_HUMAN
UniprotKB:
Q2M2I8
UniParc:
UPI0001881663,
UPI0000186919
EMBL:
BC104842,
AC136007,
AC079121,
AB028971,
AC092431,
BC111965
Ensembl:
ENSG00000115977
KO:
hsa:22848
|
| Nucleutide sequences |
EMBL-CDS:
AAI11966.1,
AAX88861.1,
AAI04843.1,
BAA83000.2,
AAY14931.1
Ensembl_TRS:
ENST00000406297,
ENST00000409085
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000385181,
ENSP00000386456
RefSeq:
NP_055726.4,
NP_001358506.1,
NP_001358504.1
|
| Others |
UniRef100:
UniRef100_Q2M2I8
UniRef90:
UniRef90_Q2M2I8
UniRef50:
UniRef50_Q2M2I8
UniGene:
Hs.468878
CCDS:
CCDS1893.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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