| Type | Description |
|---|---|
| Definition | autophagy/beclin 1 regulator 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-14 11:45:00 | GIT1 interacted with Beclin1 and promoted Beclin1 phosphorylation at Thr119, which induced the disruption of Beclin1 and Bcl2 binding under starvation conditions, thereby, positively regulating autophagy. Taken together, the findings suggest a previously unappreciated role of GIT1 in autophagy of OCs during fracture repair | 30546041 |
| 2019-06-01 11:06:00 | MG53 overexpression could promote the expression of Ambra1 in C2C12 cells and restore mitochondrial autophagy. | 30614598 |
| 2018-12-22 10:15:00 | these findings identify an Ambra1-dependent mechanism that drives inhibition/excitation imbalance in the hippocampus, contributing to abnormal brain activity reminiscent of neurodevelopmental disorders. | 29488136 |
| 2018-08-04 10:12:00 | Results showed that AMBRA1 is a novel hub binding protein of alpha-synuclein and plays a central role in the pathogenesis of multiple system atrophy through the degradative dynamics of alpha-synuclein. | 27875637 |
| 2018-07-21 11:15:00 | MicroRNA-30a ameliorates hepatic fibrosis by inhibiting Beclin1-mediated autophagy. | 28766848 |
| Type | IDs |
|---|---|
| Synonymous | 2310079H06Rik, A130023A14, AA474864, AV021921, D030051N19Rik, mKIAA1736 |
| Gene |
UniProtKB-ID:
AMRA1_MOUSE
UniprotKB:
A2AH22
UniParc:
UPI000002719D,
UPI0000193CE7,
UPI00005AC82C,
UPI00005B254E,
UPI00000EA4C3,
UPI0000D7786E,
UPI0000D7786F
EMBL:
AK148887,
AL731772,
AK155513,
AL714023,
AK083596,
AK169280,
AK129433,
AK037516
Ensembl:
ENSMUSG00000040506
KO:
mmu:228361
|
| Nucleutide sequences |
EMBL-CDS:
BAC98243.1,
BAC38965.1,
BAE41038.1,
BAE33303.1,
BAE28691.1,
BAC29823.1
Ensembl_TRS:
ENSMUST00000111316,
ENSMUST00000099712,
ENSMUST00000111317,
ENSMUST00000045705,
ENSMUST00000045699
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000048898,
ENSMUSP00000049258,
ENSMUSP00000106949,
ENSMUSP00000106948,
ENSMUSP00000097299
RefSeq:
NP_766257.3,
NP_001074223.1,
XP_006499316.1,
XP_006499315.1
|
| Others |
UniRef100:
UniRef100_A2AH22
UniRef90:
UniRef90_A2AH22
UniRef50:
UniRef50_Q9C0C7
UniGene:
Mm.436667
CCDS:
CCDS38179.1,
CCDS38180.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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