| Type | Description |
|---|---|
| Definition | purinergic receptor P2X, ligand-gated ion channel, 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:14:00 | Functional Coupling of Slack Channels and P2X3 Receptors Contributes to Neuropathic Pain Processing. | 33401689 |
| 2018-07-28 10:47:00 | This study demonstrated that the P2X3-immunoreactive nerve endings in the rat tracheal mucosa have unique morphological characteristics, and these endings may be rapidly adapting receptors and/or irritant receptors that are activated by mucosal irritant stimuli. | 29124772 |
| 2017-07-15 10:48:00 | Data suggest that the negative inhibition of P2X3R activity by the BNP/NPR-A pathway results in a decreased P2X3R-mediated excitability of trigeminal neurons in wildetype cultures. In familial hemiplegic migraine type-1 model cultures, however, lack of efficient P2X3Rs downregulation contributes to the neuronal hyperexcitability phenotype. | 27346147 |
| 2016-12-31 11:10:00 | P2X3 receptors on mouse trigeminal ganglion neurons are subjected to contrasting modulation by inhibitory brain natriuretic peptide and facilitatory calcitonin gene-related peptide that both operate via complex intracellular signaling. | 27175010 |
| 2016-09-24 10:46:00 | mouse trigeminal neurons endogenous BNP acts on NPR-A receptors to determine constitutive depression of P2X3 receptor function. Tonic inhibition of P2X3 receptor activity by BNP/NPR-A/PKG pathways occurs via two distinct mechanisms: P2X3 serine phosphorylation and receptor redistribution to non-raft membrane compartments | 26576636 |
| Type | IDs |
|---|---|
| Synonymous | 4930513E20Rik, P2X3 |
| Gene |
UniProtKB-ID:
P2RX3_MOUSE
UniprotKB:
Q3UR32
UniParc:
UPI000024DDA2
EMBL:
AK141847,
BC023089,
AL935159,
AK140283
Ensembl:
ENSMUSG00000027071
KO:
mmu:228139
|
| Nucleutide sequences |
EMBL-CDS:
AAH23089.1,
BAE24316.1,
BAE24856.1
Ensembl_TRS:
ENSMUST00000028465
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000028465
RefSeq:
XP_030106044.1,
NP_663501.2,
XP_030106046.1,
XP_011237754.1,
XP_030106043.1,
XP_006499273.1,
XP_030106045.1
|
| Others |
UniRef100:
UniRef100_Q3UR32
UniRef90:
UniRef90_P49654
UniRef50:
UniRef50_P56373
UniGene:
Mm.440375,
Mm.448935
CCDS:
CCDS16200.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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